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Therapeutics

The NIA Small Business Programs support small businesses who aim to develop therapeutic interventions that address factors that impact the aging population, as well as related conditions like Alzheimer’s disease and related dementias.

The small business awardees below were selected by NIH in 2019-2020 to present their groundbreaking technologies and interventions to potential partners and third-party investors at industry showcases.

Displaying 1 - 10 of 17 business showcases.

  • AgeneBio, Inc.

    AgeneBio logoRead about AgeneBio, a small business using NIA funding to develop a novel therapeutic approach that could offer success in the area of Alzheimer’s disease prevention by targeting aberrantly heightened neural activity.

  • Allyx Therapeutics, Inc.

    Allyx Therapeutics logoRead about Allyx Therapeutics, Inc., a small business using NIA funding to develop an orally bioavailable small molecule that acts as a silent allosteric modulator of metabotropic glutamate receptor 5 in order to slow Alzheimer’s disease progression.

  • AivoCode, Inc.

    AivoCode logoRead about AivoCode, Inc., a small business using NIA funding to develop a therapeutic antibody that neutralizes a novel target, CTGF, which is a hallmark of Alzheimer’s vascular dysfunction and neuroinflammation.

  • Artery Therapeutics, Inc.

    Gen-9 logoRead about Artery Therapeutics, Inc., a small business using NIA funding to develop a novel chemical entity CS6253 for the treatment of APOE4-driven dementias, including Alzheimer’s disease.

  • Calder Biosciences Inc.

    Calder Biosciences logoRead about Calder Biosciences, a small business using NIA funding to increase the shelf-life of vaccines including the highly contagious respiratory syncytial virus.

  • Cognition Therapeutics, Inc.

    Cognition Therapeutics logoRead about Cognition Therapeutics, a small business using NIA funding to develop therapeutics for Alzheimer’s disease by blocking the action of toxic oligomers on neurons.

  • DTx Pharma

    The letters D,T, and X written out with Pharma underneathRead about DTx Pharma, a small business using NIA funding to develop therapeutics for Alzheimer’s disease targeting the tau gene/protein, a driver of brain degeneration.

  • General Biophysics

    General Biophysics logoRead about General Biophysics, a small business using NIA funding to develop a treatment that is expected to lead to slowing Alzheimer’s disease progression and cognitive decline.

  • Juvena Therapeutics, Inc.

    Juvena logoJuvena Therapeutics, Inc., is a small business using NIA funding to advance a protein therapy for a rare muscle-wasting disease, myotonic dystrophy type 1 (DM1), with an orphan drug status and a more than $40 billion total addressable market (TAM).

  • Longeveron, LLC

    Longeveron written out with Biological Solutions for Aging written underRead about Longeveron, a small business using NIA funding to develop stem-cell therapy for various age-associated diseases and conditions.

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