NIA Small Business Research Contract Topics

Each year, NIH solicits contract proposals from small businesses to spur development of specific innovations that address key research and development priorities. NIA began participating in the annual NIH Small Business Innovation Research (SBIR) contracts solicitation in fiscal year 2022.

Key Dates

The NIH SBIR contracts solicitation occurs on an annual cycle. Topics are typically announced in the summer, with proposals due in the fall.

2024 proposals due: November 14, 2023

Eligibility

Small businesses eligible to apply for NIH SBIR grant funding are also eligible to apply for contract funding. The annual NIH SBIR contracts solicitation is open to current and future small businesses and entrepreneurs developing innovative technology ideas for health care.

Active NIA Contract Topics

Title	Links	Key Details
FY2024 NIH SBIR Contracts Solicitation	PHS-2024-1	Due date: November 14, 2023 Budget limits: See below

For fiscal year 2024, NIA has requested proposals for one topic:

NIH/NIA 010 - Technology to Facilitate Characterization of the Exposome in Under-Resourced Populations for AD/ADRD Studies:

Budget (total costs, per award): Phase I: $300,000 for 12 months; Phase II: $2 million for 2 years

Past NIA Contract Topics

2023 Topics

Title	Objective	Key Details
FY2023 NIH SBIR Contracts Solicitation	Conduct innovative research that will contribute toward NIH or CDC mission needs and Small Business Innovation Research (SBIR) program objectives.	Due date: November 4, 2022, 5 PM ET Budget limits: See below 2023 webinar: Archived materials

2022 Topics

View the full 2022 NIH SBIR Contracts Solicitation (PDF, 1.7M).

Title	Objective	Key Details
Improving Central Nervous System Gene Delivery Systems for Alzheimer’s Disease and Related Dementias Therapy Development	Improve gene delivery systems to overcome current challenges.	Topic number: NIH/NIA 004 Number of anticipated awards: 2-5 Budget (total costs, per award): Phase I: $500,000 for 12 months; Phase II: $2,500,000 for 2 years
Geroscience-Based Chronic Wound Treatment Product Development	Develop wound treatment that incorporates geroscience-based therapeutic modalities such as stem cell therapies, senolytics, and inflammation modulators.	Topic number: NIH/NIA 005 Number of anticipated awards: 1-2 Budget (total costs, per award): Phase I: $350,000 for 12 months; Phase II: $2,500,000 for 2 years (Phase II information is provided for informational purposes only to assist Phase I offerors with their long-term strategic planning.)
The Development of Mechanism-Based Adult Stem Cell Treatments to Combat Aging Pathologies	Develop a stem cell-based therapeutic with a defined mechanistic understanding of how it promotes regeneration and/or rejuvenation of aging tissues.	Topic number: NIH/NIA 006 Number of anticipated awards: 1-2 Budget (total costs, per award): Phase I: $350,000 for 12 months; Phase II: $2,000,000 for 2 years

Title

Objective

Key Details

Improving Central Nervous System Gene Delivery Systems for Alzheimer’s Disease and Related Dementias Therapy Development

Improve gene delivery systems to overcome current challenges.

Topic number: NIH/NIA 004
Number of anticipated awards: 2-5
Budget (total costs, per award):
- Phase I: $500,000 for 12 months;
- Phase II: $2,500,000 for 2 years

Geroscience-Based Chronic Wound Treatment Product Development

Develop wound treatment that incorporates geroscience-based therapeutic modalities such as stem cell therapies, senolytics, and inflammation modulators.

Topic number: NIH/NIA 005
Number of anticipated awards: 1-2
Budget (total costs, per award):
- Phase I: $350,000 for 12 months;
- Phase II: $2,500,000 for 2 years
- (Phase II information is provided for informational purposes only to assist Phase I offerors with their long-term strategic planning.)

The Development of Mechanism-Based Adult Stem Cell Treatments to Combat Aging Pathologies

Develop a stem cell-based therapeutic with a defined mechanistic understanding of how it promotes regeneration and/or rejuvenation of aging tissues.

Topic number: NIH/NIA 006
Number of anticipated awards: 1-2
Budget (total costs, per award):
- Phase I: $350,000 for 12 months;
- Phase II: $2,000,000 for 2 years

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Visit the Funding Opportunities page for a full list of current funding announcements.

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