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NIA Small Business Funding Opportunities

NIA participates in a broad range of funding opportunities, research and development (R&D) programs, and technical assistance that address innovations in healthy aging as well as Alzheimer’ disease (AD) and AD-related dementias (ADRD).

This page lists opportunities that are currently open for new submissions, as well as details about a select set of expired announcements. Contact the NIA Small Business Programs team to determine whether your project is a good fit for NIA.

Already an awardee? Explore our resources and innovator support programs.

NIA SBIR and STTR Omnibus Funding

This funding opportunity supports investigator-initiated small business research projects focused on a broad range of aging-related innovations that align with NIA’s research priorities. Projects focused on AD may have the best fit in AD-specific opportunities.

Title

Links

Key Details

2022 NIH SBIR/STTR Omnibus Solicitation

SBIR (PA-22-177)

STTR (PA-22-179)

Clinical trial required

Standard due dates: January 5, April 5, September 5

Budget limits: Phase I $300,000; Phase II $2 million

NIA contact: Michael-David A.R.R. Kerns

2022 NIH SBIR/STTR Omnibus Solicitation

SBIR (PA-22-176)

STTR (PA-22-178)

Clinical trial not allowed

Standard due dates: January 5, April 5, September 5

Budget limits: Phase I $300,000; Phase II $2 million

NIA contact: Michael-David A.R.R. Kerns

More Omnibus Funding Information

NIA SBIR and STTR Opportunities Targeting AD/ADRD

This type of funding announcement supports investigator-initiated small business research projects focused on developing a variety of AD/ADRD-related innovations.

Title

Links

Key Details

Advancing Research on AD and ADRD

SBIR PAS-19-316

STTR PAS-19-317

Clinical trial optional

Standard due dates: January 5, April 5, September 5

Budget limits: Phase I $500,000; Phase II $2.5 million

NIA contact: Michael-David A.R.R. Kerns

NIH Commercialization Readiness Pilot (CRP) Program

This program supports Phase II and Phase IIB awardees seeking additional capital to advance toward commercialization. CRP offers technical assistance to help develop regulatory strategy and submissions to the U.S Food and Drug Administration and other agencies. CRP also supports manufacturing, replication of key studies, compliance activities, and other commercialization readiness research.

Title

Links

Key Details

CRP Technical Assistance

SBIR & STTR PA-20-128

Clinical trial not allowed

Standard due dates: January 5, April 5, September 5

Budget limit: $300,000

NIA contact: Saroj Regmi

CRP Technical Assistance and Late Stage Development

SBIR & STTR PA-20-129

Clinical trial not allowed

Standard due dates: January 5, April 5, September 5

Budget limit: $1.75 million/year for 2 years ($3.3 million total)

NIA contact: Saroj Regmi

CRP Technical Assistance and Late Stage Development

SBIR & STTR PA-20-130

Clinical trial required

Standard due dates: January 5, April 5, September 5

Budget limit: $1.75 million/year for 2 years ($3.3 million total)

NIA contact: Saroj Regmi

NIH Special Initiatives

NIA participates in the following mission-related special initiatives and funding opportunities led by other NIH Institutes, Offices, and Centers.

Title

Links

Key Details

SBIR Technology Transfer

NOT-NS-017

Clinical trial not allowed

Standard due dates: January 5, April 5, September 5

Budget limits: Phase I $300,000; Phase II $2 million

NIA contact: Michael-David A.R.R. Kerns

Non-Viral Technologies for In Vivo Delivery of Genome Editors

SBIR PAR-20-098

STTR PAR-20-109

Clinical trial not allowed

Standard due dates: January 5, April 5, September 5

Budget limits: Phase I $300,000; Phase II $2 million

NIA contact: Michael-David A.R.R. Kerns

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management

SBIR RFA-NS-20-010

STTR RFA-NS-20-008

Clinical trial required

Standard due dates: January 5, April 5, September 5

Budget limits: Phase I $300,000; Phase II $2 million

NIA contact: Michael-David A.R.R. Kerns

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management

SBIR RFA-NS-20-011

STTR RFA-NS-20-009

Clinical trial not allowed

Standard due dates: January 5, April 5, September 5

Budget limits: Phase I $300,000; Phase II $2 million

NIA contact: Michael-David A.R.R. Kerns

NIH Administrative Supplements and Notices

Funded awardees can access additional NIA support via administrative supplements.

Title

Links

Key Details

Promoting Diversity in SBIR

SBIR & STTR PA-21-345

Clinical trial not allowed

Due dates: Rolling submissions accepted until September 10, 2024

Budget limit: $250,000 in direct costs

NIA contact: Armineh Ghazarian

Administrative Supplements to Existing NIH Grants and Cooperative Agreements to Address Unexpected Costs

PA-20-272

Clinical trial optional

Due dates: Rolling submissions accepted until October 8, 2023

Budget limit: $250,000 in direct costs

NIA contact: Saroj Regmi

Select Expired NIA Funding Opportunities

Research and Entrepreneurial Development Immersion (REDI)

REDI funding opportunities support entrepreneurial development for early-career scientists working in the fields of aging and aging-related diseases, including AD, by providing bio-entrepreneurship training that builds additional nonacademic skills for success. Learn more about REDI and view the pre-application webinar recording.

SBIR Contracts Solicitation

NIA began participating in the annual NIH SBIR contracts solicitation in fiscal year 2022. These funding opportunities aim to spur development of specific innovations that address key Institute priorities. Learn more about past NIA SBIR contract topics.

NIA Healthy Aging Start-Up Challenge and Bootcamp to Foster Diversity and Accelerate Innovation

NIA launched this Challenge in spring 2022 to stimulate innovation and foster diversity in aging research and development by providing cash prizes and non-cash prizes that will help participants overcome barriers to participating in life sciences entrepreneurship, particularly for researchers with a demonstrated need who have innovative ideas for science-driven technologies and products. Learn more about the Challenge.

Ready to apply?

Return to the NIA Small Business Main Page.