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Patient-Reported Outcomes Measurement Information System (PROMIS)

The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH-funded initiative to develop and validate patient reported outcomes (PROs) for clinical research and practice. PROMIS aims to enhance and standardize measurement of several selected PROs through both computer adaptive testing and traditional "paper and pencil" instruments.

PROMIS was established in 2004 as a cooperative network that developed and validated PROs in global health, physical function, fatigue, pain, sleep/wake function, emotional distress, and social health. Currently, the PROMIS network consists of 12 research sites and 3 administrative centers that are developing PROs in several new domains and performing validation studies of PROs in new and existing domains.

PROMIS is one of several initiatives under the NIH Common Fund. Researchers and clinicians are encouraged to consider using PROMIS tools in their studies or practices. More information about PROMIS, including item banks, PRO instrument forms, and Assessment Center™, is available at

Direct NIA-relevant questions about PROMIS to: Basil Eldadah, MD, PhD; 301-496-6761;

Division of Geriatrics and Clinical Gerontology Research Tools and Standards DGCG NIH Common Fund PROMIS Health Databases