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Milestone 6.H

Initiate interdisciplinary research programs that integrate clinical, genomic and mechanistic research including cutting edge systems biology approaches to gain an in depth understanding of the mechanisms by which various non-pharmacological interventions impact brain health and the course of AD and AD-related dementias.


Success Criteria

  • Identification of at least 3 new therapeutic targets for neuroprotection based on knowledge of mechanisms mediating the impact of non-pharmacological interventions of brain health in aging, AD and AD-related dementias.
  • Preclinical proof-of-concept for at least 3 types of non-pharmacological interventions that can inform clinical trial design.


Research Implementation Area
Drug Development - Novel Targets
Timeline
2016–2023
Status
In Progress

Implementation Activities

Funding Initiatives

Relevant Recommendations