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Milestone 5.C

Initiate phase III drug trials for agents against at least 3 currently known therapeutic targets. Of these, at least one trial will be asymptomatic, at risk populations. These trials will incorporate a combination of biomarkers (fluid and imaging) and cognitive measures as outcomes and include collection of DNA and other bio-samples for interrogation of responsiveness. 

Success Criteria

  • Comprehensive success/failure analysis of data from at least 3 phase III trials.

Research Implementation Area
Drug Development - Existing Targets
In Progress

Accomplishments/Implementation Activities

Funding Initiatives

Research Programs and Resources

Relevant Recommendations