Translational Capabilities: Training programs (Milestone 4.J)
In Progress
Timeline Start - End
2016 - 2024Research Implementation Area
Translational Tools, Infrastructure, and CapabilitiesExpand existing and create new integrative training programs for early career neuroscience, behavioral and social science researchers that include training in aging biology, systems biology, geriatrics, all aspects of data science as well as traditional and emerging drug discovery disciplines. These efforts should include cross-disciplinary training programs in AD, aging, epidemiology, neuropsychology, environmental health, genomics, and data science to enhance the workforce needed for research on gene-environment interactions in AD and AD health disparities.
Success Criteria
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Enhance existing and establish new institutional training programs as well as fellowship and career development programs to develop a diverse translational and data science workforce.
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Create a series of cross-disciplinary career development programs in AD/ADRD for early-stage scientists that are under-represented in the scientific workforce.
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Use multiple funding mechanisms such as training and conference grants, to promote the adoption of best practices for rigorous and reproducible research and propagation of open science principles among early career scientists.
Summary of Key Accomplishments
NIA supports multiple opportunities for interdisciplinary training and career development for junior investigators. One example is the AD-focused Resource Centers for Minority Aging Research (RCMARs), which are designed to enhance the diversity of the aging research workforce by mentoring promising early-stage scientists from underrepresented groups for careers in aging research in priority areas of social, behavioral, and economic research on AD/ADRD.
The Institutional Training Programs to Advance Translational Research on Alzheimer's Disease and AD-Related Dementias provide junior investigators with the knowledge and skills necessary to conduct rigorous and cutting-edge translational research for AD/ADRD. Eleven training programs have been established via this initiative. NIA has also issued opportunities for short interdisciplinary courses offered to a wide range of researchers, including junior investigators, on a variety of topics Collectively, these initiatives aim to enable the development of a diverse research workforce that can effectively participate in, and/or lead impactful research in AD/ADRD.
The key accomplishments summary is current as of July 2022.
Accomplishments/Implementation Activities
Funding Initiatives
- PAR-17-052: Research Career Enhancement Award to Advance Therapy Development for Alzheimer's (K18)
- RFA-AG-17-063: Institutional Training Programs to Advance Translational Research on Alzheimer’s Disease and AD Related Dementias (T32)
- PAR-18-524: Institutional Training Programs to Advance Translational Research on Alzheimer's Disease and AD Related Dementias (T32)
- PAR-21-112: Institutional Training Programs to Advance Translational Research on Alzheimer’s Disease and AD Related Dementias (T32)
- RFA-AG-18-002: Alzheimer’s-Related Resource Centers for Minority Aging Research (AD-RCMAR) (P30)
- RFA-AG-19-001: Alzheimer's Disease Research Centers (P30)
- RFA-AG-20-004: Alzheimer's Disease Research Centers (P30)
- RFA-AG-19-007: Roybal Centers for Translational Research on Dementia Care Provider Support (P30)
- RFA-AG-20-031: Research Education: Short Courses on Alzheimer's Disease and Related Dementias for the Behavioral and Social Sciences (R25 Clinical Trial Not Allowed)
- RFA-AG-20-032: MD-PhD Training Program in Alzheimer's Disease and Its Related Dementias and the Behavioral and Social Sciences (T32)
- RFA-AG-21-027: MD-PhD Training Program in Alzheimer's Disease and Its Related Dementias and the Behavioral and Social Sciences (T32)
- PAS-19-391: Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research: Area of Focus Archiving and Leveraging Existing Data Sets for Analyses (Reissue of RFA-AG-19-003)
- NOT-AG-21-027: Notice of Participation of the National Institute on Aging (NIA) in PAR-21-230 "Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43 Clinical Trial Optional)
- PAR-21-141: AD/ADRD Clinical Trials Short Course (R25)
- RFA-AG-22-010: Short Courses on Interdisciplinary Behavioral and Social Sciences Research on ADRD (R25)
- PAR-21-112: Institutional Training Programs to Advance Translational Research on Alzheimer's Disease (AD) and AD-Related Dementias (T32)
- PAR-21-217: NIA Postdoctoral Fellowship Award to Promote Diversity in Translational Research for AD/ADRD (F32 Clinical Trial Not Allowed
- PAR-21-218: NIA Predoctoral Fellowship Award to Promote Diversity in Translational Research for AD/ADRD (F31)
- PAR-21-220: NIA Advanced Postdoctoral Career Transition Awards to Promote Diversity in Translational Research for AD/ADRD (K99/R00 Clinical Trial Not Allowed)
Research Programs and Resources
- Alzheimer's Disease Research Centers
- Alzheimer’s-Related Resource Centers for Minority Aging Research (AD-RCMAR)
- AD RCMAR Centers NIA Website
- RCMAR Coordinating Center Website
- AD Roybal Centers NIA website
- NIA IMPACT Collaboratory: Transforming Dementia Care
- RCMAR 2019 GSA Pre-Conference: Strategies for Successful Recruitment and Retention of Minority Elders: An NIA Priority Area
- Institutional Training Programs to Advance Translational Research on Alzheimer’s Disease and AD Related Dementias
- 2019-2021 Drug Discovery for Neurodegeneration Conferences
- ADDF 14th Annual Drug Discovery for Neurodegeneration Workshop
- Improving Preclinical Translation in Alzheimer's Disease Research
- Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT AD)
- Select projects funded in FY21
- The Agile Nudge University Program
- Projects funded under PAR-21-141 in FY22
Research Highlights
Relevant Recommendations
- 2015 AD Summit: 1.J, 4.D, and 4.E
- 2017 Dementia Care Summit: 5.4
- 2018 AD Summit: 4.N, 5.M and 6.J
- 2021 AD Summit: 1.J