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Milestone 9.C

Initiate development of imaging and/or fluid biomarkers to demonstrate target engagement for 5 novel therapeutic targets for AD and related dementias.

Success Criteria

Identification of 3 imaging and/or fluid biomarkers for which there is proof of engagement of novel therapeutic targets.

Time Required

2014 to 2018

Research Implementation Area


CADRO Category

B. Diagnosis, Assessment and Disease Monitoring

Activities, Funding Initiatives, and Resources

NIH PAR-15-359: Novel Approaches to Diagnosing Alzheimer's Disease & Predicting…

Relevant Recommendation(s)

2012 AD Summit Recommendations: 1E