Establish a searchable, open access research database that contains all clinical, biomarker, and epidemiological data, and related genotypes and phenotypes from existing genetic studies; analyze these data to identify regions of the genome that are targets for AD and ADRD therapeutics.
At least one novel target, pathway or therapeutic approach identified through use of the database.
2013 to 2020
Research Implementation Area
Drug Development - Novel Targets
C. Translational Research and Clinical Intervention
Activities, Funding Initiatives, and Resources
NIH PAR-16-047: NIA Genetics of Alzheimer’s Disease Data Storage Site
NIH RFA-AG-16-001: Coordinating Center for Genetics and Genomics of Alzheimer'…
NIH PAR-12-183: Alzheimer's Disease Sequencing Project (ADSP)
NIH RFA-AG-16-001: NIA Coordinating Center for Genetics and Genomics of Alzheim…
NIH PAR-17-214: Limited Competition: Analysis of Data from NIA's Alzheimer's Di…
NIH RFA-AG-18-013: Continuation of the AMP-AD Target Discovery and Preclinical …
NIH RFA-AG-18-014: Limited Competition: Data Coordinating Center for the Accele…