AD Related Dementias – Specific
Encourage crosstalk and interdisciplinary collaboration between TBI and dementia researchers.
- Convene a working group of stakeholders from the TBI and AD/ADRD communities, including trainees, to evaluate the extent to which current knowledge in AD/ADRD can be applied to the study of dementia after TBI. This working group can assess the level of data harmonization across existing TBI and dementia clinical cohort studies to facilitate current and future comparisons and data sharing.
- Support the addition of interdisciplinary retrospective assessment for TBI history and prospective TBI occurrence in existing AD/ADRD cohort studies.
- Support the addition of AD/ADRD assessments to existing TBI cohort studies.
Summary of Key Accomplishments
NIH’s AD/ADRD program is exploring opportunities to develop cross-training and career enhancement programs such as K (PAR 19-238) awards. These opportunities have the potential to bring junior researchers with a diverse scientific background (e.g., TBI) into the field of AD/ADRD. In an effort to encourage interdisciplinary collaborations, NINDS also seeks opportunities to support existing TBI and AD/ADRD cohort studies such as NOT-NS-22-002.
This information is current as of July 2022.
- Research Implementation Area
- AD Related Dementias - Specific
- In Progress
- RFA-NS-19-026: Clinical and Biological Measures of TBI-related dementia including Chronic Traumatic Encephalopathy (CTE) (R01)
- RFA-NS-19-030: Neuropathological Assessment of TBI-related Neurodegeneration and Neurocognitive Decline - Center Without Walls (NATBI CWOW) (U54)
Research Programs and Resources
- NINDS Common Data Element Program
- Federal Interagency TBI Research (FITBIR) database
- Clinical and Biological Measures of TBI-related dementia including Chronic Traumatic Encephalopathy (CTE) (R01)
- Neuropathological Assessment of TBI-related Neurodegeneration and Neurocognitive Decline - Center Without Walls (NATBI CWOW) (U54)
- The Neuropathological Diagnosis of Chronic Traumatic Encephalopathy (CTE): Next Steps