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Milestone 1.M

AD Related Dementias – Specific

Understand phenotypic heterogeneity and natural history including in populations that experience health disparities.


Success Criteria

  • Support natural history studies of preclinical inherited FTD, by following individuals from health to disease.
  • Support natural history studies of sporadic FTLD, starting from early symptomatic FTD and prioritizing clinical syndromes for which the clinico-pathological correlation is high.

Summary of Key Accomplishments

The ALLFTD study is a comprehensive natural history study covering inherited forms of FTD, where individuals have been followed from health to disease. Important findings from this study have shown that the type of causative mutation has a major impact on disease progression and biomarkers of disease progression.

This information is current as of July 2022.


Research Implementation Area
AD Related Dementias - Specific
Timeline
2016–2025
Status
Achieved

Accomplishments/Implementation Activities

Funding Initiatives

Research Programs and Resources

Research Highlights

Relevant Recommendations

nia.nih.gov

An official website of the National Institutes of Health