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Milestone 4.V

ADRD Specific Milestone

Build new animal models to advance knowledge about TDP-43 pathology in common dementias, capitalizing on lessons learned from animal models in FTLD/ALS, AD and other diseases.


Success Criteria

  • Develop, validate and make available to the broader scientific community two or more novel animal models that exhibit TDP-43 pathology aligned with the affected anatomical sites and functional changes that occur in common dementias such as the clinical syndrome of Alzheimer’s disease.


Research Implementation Area
AD Related Dementias - Specific
Timeline
2020–2027
Status
In Progress

Accomplishments/Implementation Activities

Funding Initiatives

Research Programs and Resources

Relevant Recommendations