Leverage the power of human genetics to enable precision medicine research for AD by:
- improving the accessibility of large-scale AD genetics data
- expanding genetics efforts across AD and ADRD cohorts, as open science programs, similar to the Psychiatric Genetics Consortium and AMP-T2D consortia, and
- encouraging commercial entities to share genetic data.
Support a large-scale, coordinated, genotyping/sequencing effort across AD and ADRD cohorts.
Develop an Open Access aggregated genetics data search engine/portal for Alzheimer’s and related disorders (akin to the AMP-T2D portal) to facilitate access to genetic data and analyses by the wide research community and to enable commercial entities to share genetic data.
- Research Implementation Area
- Translational Tools, Infrastructure and Capabilities
- In Progress
- PAR-16-047: The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) (U24)
- PAR-16-205: The National Institute on Aging (NIA) Late Onset of Alzheimer's Disease (LOAD) Family Based Study (FBS) (U24)
- PAR-16-406: Limited Competition: Additional Sequencing for the Alzheimer's Disease Sequencing Project (U01)
- RFA-AG-16-001: NIA Coordinating Center for Genetics and Genomics of Alzheimer's Disease (U54)
- RFA-AG-16-002: Alzheimer's Disease Sequencing Project (ADSP) Replication Phase Analysis Studies (U01)
- PAR-17-214: Limited Competition: Analysis of Data from NIA's Alzheimer's Disease Sequencing Project Follow-Up Study (U01)
- PAR-18-889: Limited Competition: Renewal of, and Revisions to, the Alzheimer's Disease Genetics Consortium (U01)
Research Programs and Resources
- NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS)
- Alzheimer’s Disease Sequencing Project
- Alzheimer’s Disease Genetics Consortium
- Genome Center for Alzheimer’s Disease