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Milestone 2.F

Create new research programs aimed at understanding the integrative physiology of circadian rhythms and sleep and its impact on brain aging and the risk of AD and AD-related dementias at multiple levels (epigenetic, gene expression, proteomic, neuronal, network, systems) to identify new targets and approaches for AD prevention.


Success Criteria

  • Launch at least 12 new projects focused on understanding the short-term and long-term consequences of disrupted/optimized circadian rhythms and sleep on brain aging and dementia and the mechanistic links between sleep/circadian disruption and AD and AD-related dementias to identify new targets and approaches for AD prevention.


Research Implementation Area
Research on Disease Mechanisms
Timeline
2016–2023
Status
In Progress

Implementation Activities

Funding Initiatives

Research Programs and Resources

Research Highlights

Relevant Recommendations