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Multiple Etiology Dementias: Support research on early detection of cognitive impairment/dementia in everyday settings (Milestone 9.K)

In Progress

Timeline Start - End

2016 - 2027

Research Implementation Area


AD-Related Dementias Focus

Evaluate pragmatic approaches to objectively detect cognitive impairment and link to quality care when a patient, care partner, or clinician reports cognitive, behavioral, or functional changes.   

Success Criteria

  • Complete at least three clinical trials to validate assessment paradigms to detect cognitive impairment in large and diverse populations in primary care practice and other every day clinical care settings. 

Summary of Key Accomplishments

DetectCID (RFA-NS-17-012 & RFA-NS-22-009) is improving the quality of patient evaluations for detecting cognitive impairment in everyday clinical settings. For example, researchers created a new set of easy-to-use, 5-minute screening tools designed for use across languages and cultures. The UCSF Brain Health Assessment has developed and validated a 10 minute, tablet-based system to differentially diagnose different types of mild cognitive impairment. The NIH has also invested in research and validation of mobile tools for detection of cognitive impairment under RFA-AG-18-012 and started to validate them in existing cohorts. These efforts are on on-going, pivoting to a focus on pragmatic clinical trials.

The key accomplishments summary is current as of July 2022.  

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