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MED-LATE: Differential diagnosis (Milestone 11.M)

In Progress

Timeline Start - End

2022 - 2029

Research Implementation Area

Enabling Technologies and Disease Monitoring

AD-Related Dementias Focus

Define LATE (pathologic, clinical, genetic, molecular) classification and diagnostic boundaries across FTLD-TDP, AD and other dementia related pathologies and their syndromes to enhance diagnosis, research, and awareness assuring diversity, inclusion, and equity.  

Success Criteria

  • Develop and publish a report that defines limbic-predominant age-related TDP-43 encephalopathy (LATE) classification and diagnostic boundaries (pathologic, clinical, genetic, molecular) across FTD, AD and other dementia diagnoses, other nervous system disorders with TDP-43 proteinopathies, and in diverse populations.

Summary of Key Accomplishments

This milestone has just been initiated. Accomplishments are forthcoming.

The key accomplishments summary is current as of November 2022.

Accomplishments/Implementation Activities

Research Highlights

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