MED-LATE: Differential diagnosis (Milestone 11.M)
Timeline Start - End2022 - 2029
Research Implementation AreaEnabling Technologies and Disease Monitoring
AD-Related Dementias Focus
Define LATE (pathologic, clinical, genetic, molecular) classification and diagnostic boundaries across FTLD-TDP, AD and other dementia related pathologies and their syndromes to enhance diagnosis, research, and awareness assuring diversity, inclusion, and equity.
- Develop and publish a report that defines limbic-predominant age-related TDP-43 encephalopathy (LATE) classification and diagnostic boundaries (pathologic, clinical, genetic, molecular) across FTD, AD and other dementia diagnoses, other nervous system disorders with TDP-43 proteinopathies, and in diverse populations.
Summary of Key Accomplishments
This milestone has just been initiated. Accomplishments are forthcoming.
The key accomplishments summary is current as of November 2022.
- 2022 ADRD Summit: Multiple Etiology Dementias (MED) Special Topic: LATE (TDP-43 in Common Late Onset Dementias) Milestone 1, Priority 1