Health Equity: Develop early cognitive assessment tools for diverse populations (Milestone 11.H)
Timeline Start - End2016 - 2025
Research Implementation AreaEnabling Technologies and Disease Monitoring
AD-Related Dementias Focus
Improve AD/ADRD assessment tools (cognitive, biomarkers, -omics) and analytic methods to enhance generalizability and equity of scientific research.
- At least two research programs to develop and validate culturally informed assessment tools to detect early cognitive changes including non-English-speaking people and people with varying levels of education.
- At least one new study that that determines relationships among genes, environmental, and other biological factors that impact AD/ADRD risk and outcomes in diverse populations.
Summary of Key Accomplishments
NINDS continues to support DetectCID, a national consortium which is developing, testing, and validating several novel cognitive impairment assessments that are simple, culturally appropriate, and easy to administer in primary care and other everyday clinical settings. Now in phase 2, DetectCID is broadening the testing and validation of these assessments with a larger number of research participants – at least half of which are from racial/ethnic minority groups. It is likely to take a few more years to fully determine how effective and culturally appropriate these assessments are, but preliminary data are encouraging.
The key accomplishments summary is current as of July 2022.
- RFA-NS-17-012: Detecting Cognitive Impairment, Including Dementia, in Primary Care and Other Everyday Clinical Settings for the General Public and in Health Disparities Populations (UG3/UH3)
- NOT-NS-21-047: Administrative Supplements to Promote Diversity for NINDS Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD) Awardees
Research Programs and Resources
- Diverse VCID: White Matter Lesion Etiology of Dementia in Diverse Populations
- Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on Recovery (DISCOVERY)
- Select projects funded in FY21
- 2019 ADRD Summit: Health Disparities (HD), Focus Area 1: Assessment, Milestone 1
- 2022 ADRD Summit: Health Equity in AD/ADRD, Milestone 5