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Staff Scientist - Laboratory of Molecular Biology and Immunology

Position Description:  

The National Institute on Aging (NIA), Intramural Research Program (IRP), a major research component of the National Institutes of Health (NIH) in the Department of Health and Human Services (DHHS), is recruiting a Staff Scientist in the Gene Regulation Section (GRS) of the Laboratory of Molecular Biology and Immunology (LMBI) in Baltimore, MD. The GRS in LMBI has three major interests: 1) to understand molecular mechanisms, including 3-dimensional genome structures, that are involved in regulating B lymphocyte lineage-specific genes during development and aging; 2) to study mechanisms and functions of the transcription factor NF-κB in immune cells; and 3) to study the human immune system and changes that occur during aging. Excellent written and oral (English) communication skills are also required. The incumbent will have a major role in assisting the Laboratory Chief in the use of computational and statistical methods for analyses of genome-wide datasets and high-resolution live cell imaging. The ideal candidate will have demonstrated expertise in computational biology for analysis of large-scale datasets derived from genomics, epigenomics, microscopy, and flow cytometry. The Staff Scientist will advise and support laboratory investigations involving high-throughput DNA sequencing (ChIP-Seq, ATAC-Seq, RNA-Seq and Hi-C) and be involved in developing new methodologies and computational approaches. The candidate will have strong inter-disciplinary experience in bioinformatics and computational biology, and advanced understanding in the analysis and integration with other large-scale databases from sources such as ENCODE.

Qualified candidates must have a Ph.D. or equivalent doctoral degree in computational biology, bioinformatics, mathematics, or a related field, with productive postdoctoral experience as evidenced by an extensive record of collaborative and primary authorship in peer-reviewed publications in internationally recognized journals. Programming proficiency in more than one of the commonly used languages such as C++, Python, Perl, R, and MATLAB in a Unix environment is required. Database management experience will be considered a plus. Knowledge and familiarity of widely used genomics-related software tools are expected. Bioinformatics software development experience as evidenced by publicly deposited computational packages will be highly valued.

Staff Scientists do not receive independent resources, although they often work independently and have sophisticated skills and knowledge essential to the work of the Laboratory. Although this Staff Scientist will be supervised by the Laboratory Chief, they will be interacting with the scientists from the IRP and scientific community at large. The successful candidate will have experience in collaborative research documented in publications and more generally will have a history of publications that reflect experience in the analytical requirements of this position.

Salary is commensurate with research experience and accomplishments. A full Civil Service package of benefits (including retirement, health, life, and long-term care insurance, Thrift Savings Plan participation, etc.) is available. All employees of the Federal Government are subject to the conflict of interest statutes and regulations, including the Standards of Ethical Conduct. Additional information regarding the NIA IRP is available at the following website:

To apply: Please send a cover letter, curriculum vitae, bibliography, statement of research interests, and three letters of recommendation to: Angela Prazak, Intramural Program Specialist; Office of the Scientific Director; Vacancy # NIA-IRP-20-11; National Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, Suite 100, Room 04C230, Baltimore, MD 21224 or email Applications must reference the Vacancy # NIA-IRP-20-11. The first round of review of applications will begin on or around April 4, 2020. Applications will be accepted until the position is filled.

DHHS and NIH are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs.