Research and Funding

Funding Opportunities

Low-Cost, Pragmatic, Patient-Centered Randomized Controlled Intervention Trials (UH2/UH3)

Funding Number: RFA-HL-14-019
Funding Type:
Release Date: November 7, 2013
Expiration Date: January 24, 2014
Web Site:

This NIH Funding Opportunity Announcement (FOA) invites applications to plan and conduct low-cost, pragmatic randomized controlled trials (RCTs). Pragmatic RCTs seek to determine the effectiveness of an intervention in a real world setting. Trials proposed under this FOA should answer questions that are high impact to patients or health care providers, and must leverage existing clinical practice settings and/or existing electronic resources such as registries for the conduct of clinical trials. Trials must include features such as randomization at the point of patient care; data collection integrated into or obtained from routine clinical records or similar existing electronic resources; minimal eligibility criteria, and interventions delivered as part of routine clinical care.