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NIA Intervention Testing Program Solicits Recommendations for Compounds to Test for Anti-Aging Activity in Mice

Funding Number: NOT-AG-12-010
Funding Type: NOT
Release Date: July 3, 2012
Expiration Date: January 1, 2019
Web Site: http://grants.nih.gov/grants/guide/notice-files/NOT-AG-12-010.html
NIA Intervention Testing Program Solicits Recommendations Compounds Test Anti-Aging Activity Mice Notice Number: NOT-AG-12-010 Key Dates Release Date: July 3, 2012 Deadline Receipt Date:  September 21, 2012 Issued National Institute Aging NIA) Purpose National Institute Aging NIA) Interventions Testing Program ITP) established test compounds purported extend lifespan and/or delay onset disease disability.  NIA ITP tests such compounds mice, using variety measured endpoints assess efficacy interventions.  Three funded awards perform testing, at University Michigan, at University Texas Health Sciences Center-San Antonio, one the Jackson Laboratory.  is anticipated 3-5 compounds be accepted study 2013. ITP a collaborative effort between study sites external investigators sponsor interventions the study.  sponsor’s role to provide rationale investigating intervention, recommendations the dose, route timing administration the intervention, propose assays measurements document efficacy the intervention.  sponsor have access all data developed the treated mice, assist analysis the data will a co-author resulting publications.  Sponsors' concepts specific interventions reviewed an Access Panel accepted interventions prioritized the ITP Steering Committee. NIA ITP soliciting interventions external investigators sponsors) enter study 2013.  deadline receipt September 21, 2012.  Information the NIA ITP guidelines intervention protocol development posted at: http://www.nia.nih.gov/research/dab/interventions-testing-program-itp. Inquiries Please direct inquiries to: Nancy L. Nadon, Ph.D. Chief, Biological Resources Branch Division Aging Biology National Institute Aging 7201 Wisconsin Ave., GW 2C231 Bethesda, Maryland 20892 Phone: 301-402-7744 FAX: 301-402-5997 nadonn@nia.nih.gov