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Request for Proposals (RFP): NIA Intervention Testing Program Solicits Proposals for Compounds to Test for Anti-Aging Activity in Mice

Funding Number: NOT-AG-10-008
Funding Type: NOT
Release Date: July 29, 2010
Expiration Date: January 1, 2019
Web Site: http://grants.nih.gov/grants/guide/notice-files/NOT-AG-10-008.html
Request Proposals RFP): NIA Intervention Testing Program Solicits Proposals Compounds Test Anti-Aging Activity Mice Notice Number: NOT-AG-10-008 Key Dates Release Date: July 29, 2010 Issued National Institute Aging NIA), http://www.nia.nih.gov/) National Institute Aging NIA) Interventions Testing Program ITP) established test compounds purported extend lifespan and/or delay onset disease disability.  NIA ITP tests such compounds mice, using variety measured endpoints assess efficacy interventions.  are three sites perform testing, at University Michigan, at University Texas Health Sciences Center-San Antonio, one the Jackson Laboratory.  is anticipated 3-5 compounds be accepted study 2011. ITP a collaborative effort between study sites the sponsors propose interventions study.  sponsor’s role to provide rationale investigating intervention, recommendations the dose, route timing administration the intervention, propose assays measurements document efficacy the intervention.  sponsor have access all data developed the treated mice, assist analysis the data will a co-author resulting publications.  Proposals specific interventions reviewed an Access Panel accepted protocols prioritized the ITP Steering Committee. NIA ITP soliciting proposals compounds enter study 2011.  deadline receipt proposals December 17, 2010.  Information the NIA ITP guidelines proposal development posted at: http://www.nia.nih.gov/ResearchInformation/ScientificResources/Intervent... Inquiries Questions be directed to: nbsp;  Nancy L. Nadon, Ph.D. Chief, Biological Resources Branch Biology Aging Program National Institute Aging 7201 Wisconsin Ave., Room 2C231 Bethesda, Maryland 20892 Phone: 301-402-7744 FAX: 301-402-5997 nadonn@nia.nih.gov