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NIA Intervention Testing Program Solicits Proposals for Compounds to Test for Anti-Aging Activity in Mice

Funding Number: NOT-AG-11-006
Funding Type: NOT
Release Date: April 27, 2011
Expiration Date: January 1, 2020
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NIA Intervention Testing Program Solicits Proposals Compounds Test Anti-Aging Activity Mice Notice Number: NOT-AG-11-006 Key Dates Release Date: April 27, 2011 Issued National Institute Aging NIA), Purpose National Institute Aging NIA) Interventions Testing Program ITP) established test compounds purported extend lifespan and/or delay onset disease disability.  NIA ITP tests such compounds mice, using variety measured endpoints assess efficacy interventions.  are three sites perform testing, at University Michigan, at University Texas Health Sciences Center-San Antonio, one the Jackson Laboratory.  is anticipated 3-5 compounds be accepted study 2012. ITP a collaborative effort between study sites the sponsors propose interventions study. sponsor’s role to provide rationale investigating intervention, recommendations the dose, route timing administration the intervention, propose assays measurements document efficacy the intervention.  sponsor have access all data developed the treated mice, assist analysis the data will a co-author resulting publications.  Proposals specific interventions reviewed an Access Panel accepted protocols prioritized the ITP Steering Committee. NIA ITP soliciting proposals compounds enter study 2012.  deadline receipt proposals September 9, 2011.  Information the NIA ITP guidelines proposal development posted at: Inquiries Questions be directed to: nbsp;  Nancy L. Nadon, Ph.D. Chief, Biological Resources Branch Biology Aging Program National Institute Aging 7201 Wisconsin Ave., Suite 2C231 Bethesda, Maryland 20892 Phone: 301-402-7744 FAX: 301-402-5997