Virtual Workshop on Modeling Basic Mechanisms of Brain Aging and Alzheimer's Disease In Vitro and In Silico

Target Audience

Researchers interested in learning more about modeling basic mechanisms of brain aging and Alzheimer’s disease in vitro and in silico are invited to join this workshop.

Dates

April 27, 2022, 11:00 a.m.–3:30 p.m. ET

April 28, 2022, 11:00 a.m.–3:30 p.m. ET

Location

This workshop was held virtually on Zoom.

Purpose and Goals

On April 27 and 28, 2022, NIA hosted a virtual workshop on modeling basic mechanisms of brain aging and Alzheimer’s in vitro and in silico, exploring the state of the science, as well as the opportunities and challenges, in areas such as:

• What can in vitro “AD-in-a-dish” or population-level “village-in-a-dish” approaches tell us about the underlying mechanisms driving brain aging and Alzheimer’s?
• To what extent are human induced pluripotent stem cells (iPSCs) and brain organoids reflective of their donors’ age, neuropathology, and cognitive status?
• How might in vitro research intersect with simulated models and computational approaches to help us understand mechanisms driving brain aging and Alzheimer’s in silico?
• How can existing structures be leveraged to evaluate the neuroethical considerations accompanying this type of research?

Contact Information

Please contact Dr. Amanda DiBattista for questions you may have about the workshop.