Virtual Workshop on Microphysiological Systems to Advance Precision Medicine for Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) Treatment and Prevention

On July 19-20, 2022, NIA hosted a virtual workshop on microphysiological systems to advance precision medicine for Alzheimer's disease (AD) and AD-related dementias (ADRD) treatment and prevention. The virtual workshop brought together representatives from academia, biopharmaceutical companies, NIH and FDA to discuss advances and challenges in development and use of microphysiological systems — including organoids, organ-on-chips, and iPSC platforms — as translational tools for precision medicine research and drug development for AD/ADRD.

The workshop focused on topics around:

• Use of 2D and 3D in vitro systems for modeling disease complexity, target validation and drug screening
• Use of microphysiological systems as tools for predictive drug development
• Overview of the NCATS Tissue Chip Program
• Discussion of the regulatory perspective on the use of microphysiological systems for therapeutic development

View the workshop report (PDF, 587K).

If you have any questions about the workshop, please contact Zane Martin.