Clinical Interventions and Diagnostics Branch

The Clinical Interventions and Diagnostics Branch supports research on the prevention, treatment, and management of individuals with or at-risk for cognitive decline, Alzheimer's disease, and related dementias. The branch supports all stages of clinical development for pharmacologic and nonpharmacologic interventions and combination therapies, as well as research on methods development and training for innovative trial design. The branch also supports research on diagnostics aimed at the development and evaluation of reliable and valid multidimensional diagnostic procedures and instruments, including imaging, fluid and digital biomarkers, and clinical and neuropsychological instruments for diagnosis, progression, and response to treatment. A central goal of the branch is the maintenance and development of research infrastructure for clinical trials and biomarkers development, which includes the national network of Alzheimer’s Disease Research Centers.