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Workshop: Biological Damage and Aging

On December 11, 2019, the Longevity Consortium and NIA held a workshop on biological damage and human aging. Aging, particularly in long-lived species, involves the accumulation of damage to molecules, cellular structures, and tissue. Some is irreparable and may limit functional lifespan. The premise of the workshop was that aging-related biological damage had not been well characterized, particularly in humans. Studies in humans with some parallel studies in a range of animal species are underway that offer opportunities to measure an array of markers of biological damage. The goals of the workshop were to describe the types of molecular damage that occurs in humans – and animals – with aging and how they can be measured; in addition, the workshop proposed specific assays to be done in the ongoing studies.

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