Division of Geriatrics and Clinical Gerontology
The Division of Geriatrics and Clinical Gerontology (DGCG) supports clinical and translational research on health and disease in the aged, and research on aging over the human life span, including its relationships to health outcomes. DGCG foci include translational research for the development of new interventions for age-related conditions, prevention and treatment of multiple chronic conditions in the elderly, and studies that help to promote evidenced based geriatric care and inform policies affecting older adults.
Over the past years, DGCG-supported research has made advances regarding health issues facing the older population, and aging changes over the life span that affect prospects for healthy aging. New lines of research on these issues have been initiated.
Featured Funding Opportunities
This FOA is uniquely focused on animal and clinical studies which involve comparisons between juvenile versus adult states or between stages of postnatal development to identify putative JPFs and their effects on aging.
Analyses of CALERIE Data and Biospecimens to Elucidate Mechanisms of Caloric Restriction (CR)-Induced Effects in Humans (R01 and R21)
These FOAs (R01 and R21) will support ancillary studies of the CALERIE study. Research opportunities include secondary analyses of the CALERIE data sets and stored biospecimens to increase our understanding of the effects of CR on risk factors for chronic diseases and of the underlying molecular mechanisms. Original approaches may include the application of research tools to integrate the effects of CR on multiple systems, and the identification of novel molecular and therapeutic targets/CR mimetics.
Analyses of Adherence Strategies and Data Sets from CALERIE to Explore Behavioral and Psychosocial Aspects of Sustained Caloric Restriction in Humans (R01 and R21)
These FOAs (R01 and R21) support research projects involving secondary data analyses of the CALERIE Computerized Tracking System (CTS) adherence strategies and data set to explore behavioral and psychosocial aspects of sustained CR in humans, including for the prevention of weight gain. The adherence strategies and data on psychosocial variables contained in the CALERIE CTS provide a unique opportunity to explore a variety of innovative bio-behavioral research questions.