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Virtual Workshop: Animals for Geroscience: Needs for Translational and Preclinical Research

Target audience

Researchers at all career stages from academia, government, and industry with a shared interest in geroscience, the biology of aging, animal models, veterinary medicine, preclinical and clinical research, and/or the translation of aging interventions.


October 6, 2022, 10 a.m. - 5:15 p.m. ET

October 7, 2022, 10 a.m. - 5 p.m. ET


This workshop was held virtually on zoom.

Purpose and Goals

The geroscience hypothesis posits that intervening in fundamental aging processes will delay the appearance and decrease the severity of adult-onset diseases and ameliorate age-related decline in function observed in human populations. Recently, there has been a great deal of attention on leveraging geroscience insights from the laboratory to develop anti-aging or ‘geroprotective’ therapies. In order to move potentially effective therapies toward the clinic, we must understand if we currently have the appropriate animal models to effectively translate geroscience findings into effective and safe therapies for humans. To begin to address that question, the Trans-NIH Geroscience Interest Group (GSIG) hosted a virtual public workshop on the topic of Animal Models for Translational and Preclinical Geroscience Research on October 6-7, 2022.

This workshop aimed to gather background information on the use of animals in basic geroscience-focused research studies across academia, government, and industry settings. Speakers at the workshop examined the challenges and opportunities with studying a variety of animal models for translational geroscience research and the development of interventions that target fundamental aging processes.

Workshop themes included:

  • Current efforts in translational geroscience using laboratory mice, rats, domesticated animals, and non-human primates;
  • The application of comparative biology to gain new insights in geroscience;
  • The impact of nutrition and the microbiome in animal research;
  • New ways to utilize data from animals that are retired from research; and
  • An exploration of new and alternative models for translational geroscience.

Workshop Recording

Recordings from the virtual workshop are available below.

Workshop Day 1 (October 6, 2022)



Workshop Day 2 (October 7, 2022)


Contact Information

If you have any questions about the workshop, please contact Siobhan Addie.

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