Caenorhabditis Intervention Testing Program (CITP)

The NIA supports a multi-institutional Caenorhabditis Interventions Testing Program (CITP) for testing, under standardized conditions, intervention strategies that may moderate or alleviate health decline associated with aging. This program offers the research community the opportunity to submit proposals for interventions to be tested.

The CITP is a peer-reviewed program designed to identify pharmacological interventions that may moderate or alleviate health decline associated with aging in a robust manner using a genetically diverse set of Caenorhabditis species and strains. Testing is performed at three sites – Rutgers University, the University of Oregon and the Buck Institute for Research on Aging – funded through three NIA U01 cooperative agreements. Work at the three sites is coordinated by a Data Coordinating Center (DCC) located at the University of Oregon and funded through an NIA U24 cooperative agreement.

For more information, visit the CITP website.

Every year, the NIA publishes a Notice soliciting nominations for candidate compounds to enter the CITP testing pipeline. Individuals interested in submitting a nomination should read and follow the CITP Intervention Nomination Guide.