The Division of Aging Biology (DAB) promotes and supports research and training on the molecular, genetic, cellular, and physiological mechanisms underlying aging and age-related changes in humans and other organisms across numerous phyla. Support is provided for basic, applied, and translational research into mechanisms of aging from cell-autonomous actions, organelle interactions, interorgan communication, and microbiomes. These studies should uncover shared and species-specific features of aging that will lead to better identification and understanding of key biological processes that determine rates and heterogeneity of aging, and how external factors impact rates of aging. There is special emphasis for research on heterogeneity as a biological driver of divergence in health outcomes (health disparities). Geroscience research is supported to examine diverse mechanisms of interventions that impact rates of aging and health outcomes. The DAB also oversees contracts providing select biological resources for aging research.