Research and Funding

Instruments to Detect Cognitive Impairment in Older Adults

Informant Questionnaire on Cognitive Decline in the Elderly

Administration Method: 
"Or' rule: If either test (MMSE, IQCODE) is positive for dementia; "And" rule: If both tests are positive for dementia; "Weighted sum" rule: Probability of dementia calculated using sum of test scores weighted by their coefficients from logistic regression (210); 26 items (110); Questions were given to caretaker or patient (72). The IQCODE originated as an interview in which the informant was asked to rate the subject’'s improvement or decline in 26 aspects of memory and intelligence over a 10-year period. (320)
Administration Time: 
10-12 min (126); 13-24 min (110)
Level of Expertise to Administer: 
Family member (320)
Measures Change Over Time: 
Target Age Range: 
60 or older (72): with Alzheimer's disease, 69 (SD 9 yrs); with vascular dementia, 70 (SD 9 yrs); no dementia, 65 (SD 10 yrs) (210). Normal: 71.23 (SD 6.38 yrs); dementia:74.52 (SD 7.22 yrs) (159). 69 yrs, 73 yrs, 73 yrs, 75 yrs, 74 yrs, 75 yrs (110). 69 (SD 14.4 yrs) (158).
Education Level Required to Understand Test: 
Special Population Samples: 


Reference Number Title Citation PMID DOI
210 Improving detection of dementia in Asian patients with low education: combining the Mini-Mental State Examination and the Informant Questionnaire on Cognitive Decline in the Elderly. Narasimhalu K, Lee J, Auchus AP, Chen CP Dement Geriatr Cogn Disord. 2008;25(1):17-22. Epub 2007 Nov 19. 18025825 10.1159/000111128
110 Screening for dementia: a review of self- and informant-assessment instruments Nicolas Cherbuin, Kaarin J. Anstey and Darren M. Lipnicki. International Psychogeriatrics (2008), 20:3, 431–458 18289452 10.1017/s104161020800673x
72 Performance of Brazilian long and short IQCODE on the screening of dementia in elderly people with low education. Perroco TR, Bustamante SE, Moreno Mdel P, Hototian SR, Lopes MA, Azevedo D, Litvoc J, Filho WJ, Bottino CM Int Psychogeriatr. 2009 Jun;21(3):531-8. Epub 2009 Mar 27. 19323868 10.1017/s1041610209008849
320 Measuring Health: A Guide to Rating Scales and Questionnaires Ian McDowell: OXFORD Another Link
126 A review of screening tests for cognitive impairment. Cullen B, O'Neill B, Evans JJ, Coen RF, Lawlor BA J Neurol Neurosurg Psychiatry. 2007 Aug;78(8):790-9. Epub 2006 Dec 18. 17178826 10.1136/jnnp.2006.095414
159 Modified Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as a screening test for dementia for Thai elderly. Siri S, Okanurak K, Chansirikanjana S, Kitayaporn D, Jorm AF Southeast Asian J Trop Med Public Health. 2006 May;37(3):587-94. 17120985
158 The validity of brief screening cognitive instruments in the diagnosis of cognitive impairment and dementia after first-ever stroke. Srikanth V, Thrift AG, Fryer JL, Saling MM, Dewey HM, Sturm JW, Donnan GA Int Psychogeriatr. 2006 Jun;18(2):295-305. 16734921 10.1017/s1041610205002711