Research and Funding

Instruments to Detect Cognitive Impairment in Older Adults

Addenbrooke's Cognitive Examination-Revised

Administration Method: 
Oral Instruction, paper and pencil (321)
Administration Time: 
15 min (204); 12-20 min (218); 16 min (126) 12-20 (42)
Level of Expertise to Administer: 
No (218)
Measures Change Over Time: 
Target Age Range: 
Patients with corticobasal syndrome (CBS; 68 ± 8 yrs); patients with progressive nonfluent aphasia (PNFA; 68 ± 10 yrs); Control- 67 ± 4 yrs (204); Control: 64.4 (SD 5.7 yrs); with MCI: 68.8 (SD 9 yrs; with dementia: 65.7 (SD 8 yrs) (218)
Education Level Required to Understand Test: 
Special Population Samples: 


Reference Number Title Citation PMID DOI
218 The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening. Mioshi E, Dawson K, Mitchell J, Arnold R, Hodges JR Int J Geriatr Psychiatry. 2006 Nov;21(11):1078-85. 16977673 10.1002/gps.1610
32 The diagnostic accuracy of dementia-screening instruments with an administration time of 10 to 45 minutes for use in secondary care: a systematic review. Appels BA, Scherder E Am J Alzheimers Dis Other Demen. 2010 Jun;25(4):301-16. 20539025 10.1177/1533317510367485
204 Screening for cognitive dysfunction in corticobasal syndrome: utility of Addenbrooke's cognitive examination. Mathew R, Bak TH, Hodges JR Dement Geriatr Cogn Disord. 2011;31(4):254-8. Epub 2011 Apr 8. 21474935 10.1159/000327169
126 A review of screening tests for cognitive impairment. Cullen B, O'Neill B, Evans JJ, Coen RF, Lawlor BA J Neurol Neurosurg Psychiatry. 2007 Aug;78(8):790-9. Epub 2006 Dec 18. 17178826 10.1136/jnnp.2006.095414
42 Brief cognitive screening instruments: an update. Ismail Z, Rajji TK, Shulman KI Int J Geriatr Psychiatry. 2010 Feb;25(2):111-20. 19582756 10.1002/gps.2306