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NIH releases 2022 dementia research progress report

Dr. Richard Hodes
Richard J. HODES,
Office of the Director (OD)

NIH has released Advancing Alzheimer’s Disease and Related Dementias Research for All Populations: Prevent. Diagnose. Treat. Care (PDF, 17.5M), a 2022 scientific progress report. This report provides a comprehensive overview of the meaningful progress researchers made from April 2021 through March 2022 to address the enormous challenges of Alzheimer’s and related dementia diseases. A few highlights of NIH-funded progress included:

  • An anti-beta-amyloid vaccine that shows promise in people living with Down syndrome
  • A recently launched clinical trial to test gene therapy for Alzheimer’s and mild cognitive impairment
  • The first blood test for a biomarker of Alzheimer’s that is now validated in clinical trials
  • Study results that suggest a specific hormone may be key to sex differences in Alzheimer’s
  • The finding that speed of processing training may delay cognitive impairment
  • Unraveling of links between dementia and COVID-19, and other infectious diseases
  • Research that underscored how clinical trial data must be representative of all communities
  • Study results showing that for people living with dementia, having a family member available to help reduced the need for paid care
  • A new NIH intramural dementia research center designed to further accelerate a broad range of scientific discovery

FY 24 bypass budget

This year’s progress report was preceded by the Fiscal Year 2024 Professional Judgment Budget for Alzheimer’s Disease and Related Dementias announced in late July. Looking Forward: Opportunities to Accelerate Alzheimer’s and Related Dementias Research (PDF, 9.7M) provides an estimate of the funds needed to enable NIH to fully pursue scientific opportunities to inform effective prevention, treatment, and care of those living with these diseases.

Collaborate and connect to help us continue the work

Alzheimer’s and related dementias scientific progress at NIH is made possible by collaborations among researchers; clinicians; individuals living with dementia, their care partners, and their families; and the generous and sustained support of Congress. We encourage you to be part of this exciting time for science! Apply for funding or consider applying for an opportunity to work at NIA.

Together, we are accelerating Alzheimer’s and related dementias research to achieve optimal prevention, diagnostic, treatment, and care options. Check out our progress report (PDF 17.5M) and leave any questions or comments below.

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