The Wisconsin Registry for Alzheimer's Prevention: A Review of Findings and Current Directions
The Wisconsin Registry for Alzheimer's Prevention is a longitudinal observational cohort study enriched with people with a parental history of probable Alzheimer's dementia. Since late 2001, this registry has enrolled 1,561 people at a mean age of 54 years. Participants return for a second visit 4 years after baseline, then every 2 years. Eighty-one percent of participants remain active in the study after 9 years of follow-up. Assessments of cognition, self-reported medical and lifestyle histories, laboratory tests, genetics, and other procedures and data have yielded many important findings.
Johnson SC, Koscik RL, Jonaitis EM, et al. The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directions. Alzheimer's & Dementia (Amsterdam). 2017 Dec 8;10:130-142.