Recruitment Across Two Decades of NIH-Funded Alzheimer's Disease Clinical Trials

This paper examines trends in recruitment over 20 years of NIH-funded Alzheimer’s disease clinical trials conducted by the Alzheimer’s Disease Cooperative Study. The authors observed that no trial achieved an overall recruitment rate of > 1 subject per site per month. They also found that trials with no competition had the fastest recruitment and trials that overlapped with others had the slowest recruitment. 

Ritchie M, et al. Recruitment across two decades of NIH-funded Alzheimer's disease clinical trials. Alzheimers Res Ther. 2023;15(1):28. doi: 10.1186/s13195-023-01177-x.