The Effectiveness of Small-Group Community-Based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer's Disease

While recruiting for the Anti-Amyloid Treatment in Asymptomatic Disease (A4) Trial, investigators compared one-on-one with small-group recruitment sessions. Of the 127 potential participants, most chose small-group sessions. Researchers found that small-group sessions yielded a recruitment rate of 90 percent, while one-on-one sessions led to a 67 percent recruitment rate. In addition, small-group sessions contributed to significantly shorter median time for consent processes (20 versus 60 minutes) and reduced staff time spent on persons not recruited. The authors concluded that small-group education programs are an effective strategy for enhancing recruitment success and facilitating practical recruitment into clinical trials with high recruitment demands.

Tarrant SD, Bardach SH, Bates K, et al. The effectiveness of small-group community-based information sessions on clinical trial recruitment for secondary prevention of Alzheimer's disease. Alzheimer's Disease & Associated Disorders 2017;31(2):141-145.