Attitudes About Involvement in Hypothetical Clinical Trial Protocols in Mexican and Mexican-American at Risk for Autosomal Dominant Alzheimer's Disease

This study asked Mexicans and Mexican Americans at risk for autosomal dominant Alzheimer’s disease about their interest in participating in four hypothetical clinical trial scenarios, each with a different level of perceived invasiveness. The authors found that people living in rural Mexico were more willing to participate and that altruism toward future generations is a major motivation. The main reasons for refusal to participate were not wanting to undergo genetic testing and concern about adverse effects. 

Zuno-Reyes A, et al. Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer's disease. Alzheimers Res Ther. 2022;14(1):173. doi: 10.1186/s13195-022-01114-4.