Nutritional Interventions to Promote Healthy Aging Agenda
September 5-6, 2017
Lister Hill Auditorium
Bldg 38A, NIH Campus
September 5, 2017
8:00 a.m.-8:15 a.m.
Welcome and Workshop Goals
Giovanna Zappalà, Evan Hadley, NIA
8:15 a.m.-12:15 p.m.
Forum I. Caloric Restriction and Amino Acid Restriction
Panel A - Human Studies
Sai Krupa Das: Overview of CALERIE findings – Phase 1 and 2
Kevin Hall: Use of weight data to measure adherence in human trials of caloric restriction
Dennis Villareal: Effects of CR in different age groups & Comparison of CR with exercise effects
Luigi Fontana: CRonies - Long-term CR effects, Effects of higher degrees of CR & Effects of CR on aging mechanisms
Panel B - Laboratory Animal Studies of Calorie and Amino Acid Restriction: Implications for Future Human and Lab Animal Studies
Roz Anderson: Implications of nonhuman primate CR studies for human CR studies
Julie Mattison: Future needs for measures in nonhuman primate studies of CR and other dietary interventions
Chris Hine: Advances in understanding of aging mechanisms in rodents: Implications for human studies
Rochelle Buffenstein: Implications of comparative rodent biology for studies of CR and amino acid restriction
Thomas Gettys: Effects of essential amino acid restriction on metabolic health
12:15 p.m. - 1:15 p.m.
1:15 p.m. - 3:10 p.m.
Forum II. Differing Patterns of Fasting: Periodic Fasting, Intermittent Fasting, Time-Restricted Feeding
Krista Varady: Alternate-day fasting and other alternative fasting regimens: effects on age-related risk factors
Mark Mattson: Importance of the 'metabolic switch' in the health benefits of energy restriction protocols
Roman Kondratov: Interactions between calorie restriction and circadian clocks
Satchidananda Panda: Relationships of temporal feeding patterns to disease risk factors and physiologic outcomes in humans
3:10 p.m. - 3:20 p.m.
3:20 p.m. - 5:45 p.m.
Forum III - Differing Macronutrient Regimens and Dietary Patterns / Composition
Samantha Solon-Biet: Relationships of levels and proportions of dietary macronutrients to aging outcomes in laboratory animals
David J.A. Jenkins: Legumes as a protein source in plant based nutrition for healthy longevity
Edward Giovannucci: Evidence from human observational studies on effects of dietary constituents on inflammation and other aging-related processes
Neal Barnard: Whole-food plant-based nutrition interventions for the prevention of age-related chronic diseases
Bradley J. Willcox: The traditional Okinawan diet, caloric restriction, and healthy aging: Evidence from Centenarians
September 6, 2017
8:00 a.m. - 8:05 a.m.
8:05 a.m. - 10:15 a.m.
Forum IV - Interplay Between Affective and Cognitive Factors and Dietary Change: Factors Affecting Adherence, Factors Affected by Dietary Change
Don Williamson: Adherence strategies for weight loss and caloric restriction
Corby Martin: Effect of calorie restriction on psychological outcomes and eating attitudes and behaviors: Implications for interventions
Cary Savage: Motivational processes to affect eating behaviors and decision making
Bonnie Spring: Technologies to support tracking, self-regulation, and behavior change
Gabrielle (Brie) Turner-McGrievy: Emerging strategies for clinical intervention studies to change diet composition
10:15 a.m. - 10:25 a.m.
10:25 a.m. - 11:55 a.m.
Forum V – Design, Analytic, and Measurement Issues for Nutritional Interventions
Rafa de Cabo: Comprehensive measures to assess longitudinal aging changes in laboratory rodents
Lawrence Appel: Design considerations for trials of dietary change
David Allison: Causal modeling in assessing effects of nutritional interventions
11:55 a.m. - 12:55 p.m.
12:55 p.m. - 2:25 p.m.
Panel B (Forum V)
Mark Espeland: Selection of outcomes for assessing nutritional interventions to influence aging processes
William Kraus: Extrapolating dietary effects on cardiometabolic risk factors to hard cardiovascular outcomes: Implications for future studies
Susan Roberts: Studies of calorie restriction on aging factors: Implications for obesity prevention studies
2:25 p.m. - 3:30 p.m.
Open Discussion on Research Needs and Opportunities
Information for Remote Participants
This event may be streamed live through WebEx. Information on how to access it remotely may be provided upon request.