Modification of the epigenome can affect lifespan three generations later in C. elegans worms
November 17, 2011
Certain behaviors and exposure to environmental elements can have a lasting impact on gene expression by modifying chromatin at both the DNA and protein levels. These modifications comprise the field of epigenetics. Because older people have...
NIH-commissioned Census Bureau report describes oldest Americans
November 17, 2011
In 1980, there were 720,000 people aged 90 and older in the United States. In 2010, there were 1.9 million people aged 90 and older; by 2050, the ranks of people 90 and older may reach 9 million, according to a report from the U.S. Census Bureau,...
Removing nondividing, senescent cells in mice delays age-related disease
November 2, 2011
Researchers at the Mayo Clinic in Rochester, MN have found a causal relationship between senescent cells and certain age-related diseases in a mouse model, according to a report in Nature. While research on cell cultures has long suggested that...
New Go4Life campaign focuses on fitness for older adults
October 19, 2011
Being physically active is vital to maintaining health and independence as we age, and a new federal campaign for people 50 and older will help them to get active and keep going. Introduced today by the National Institutes of Health (NIH), the...
Genetic mutation linked to inherited forms of ALS, dementia
September 28, 2011
National Institutes of Health scientists and worldwide teams of researchers have identified the most common genetic cause known to date for two neurological diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The...
Pilot trial of insulin nasal-spray for Alzheimer’s yields promising results
September 12, 2011
Results of a pilot clinical trial show a nasal-spray form of insulin delayed memory loss and preserved cognition in people with cognitive deficits that range from mild cognitive impairment (MCI) to moderate Alzheimer’s disease. Researchers at...
Compound improves health, increases lifespan of obese mice
August 18, 2011
Researchers have reported that obese male mice treated with a synthetic compound called SRT1720 were healthier and lived longer compared to non-treated obese mice. The experimental compound was found to improve the function of the liver, pancreas...
Study finds fasting may help reduce negative side effects of chemotherapy
July 28, 2011
Valter Longo and colleagues proposed that a treatment used to prolong life in some laboratory organisms could offer protection against the negative effects of chemotherapy. That treatment is fasting, a special type of dietary restriction....
NIH tips for older adults to combat heat-related illnesses
July 18, 2011
Older people can face risks related to hot weather. As people age, their bodies lose some ability to adapt to heat. They may have medical conditions that are worsened by heat. And their medications could reduce their ability to respond to heat. The...
Media Availability: NIH researchers tie even sedentary employment in men to overall increased physical activity
July 12, 2011
WHAT: Employment status may be related in some ways to weekday physical activity, according to researchers at the National Institute on Aging (NIA), part of the National Institutes of Health. In a study measuring activity levels, full-time employed...