Topics of Interest: Alzheimer's
"Use it or lose it?" study suggests mentally stimulating activities may reduce Alzheimer's risk
February 12, 2002
In recent years, many of us have come to believe that doing crossword puzzles or playing cards might ward off a decline in memory or help us maintain "brainpower" as we age. Now, a new study suggests there might be some truth to...
Alzheimer's disease clinical trials expanded, expedited
September 20, 2001
As part of intensifying efforts to expand and expedite the search for Alzheimer's disease (AD) treatments, the National Institute on Aging (NIA) has awarded $54 million to support the Alzheimer's Disease Cooperative Study (ADCS), a...
New study links head injury, severity of injury, with Alzheimer's disease
October 23, 2000
A new analysis of head injuries among World War II veterans links serious head injury in early adulthood with Alzheimer's disease (AD) in later life. The study, by researchers at Duke University and the National Institute on Aging (NIA...
Nasal Alzheimer's vaccine successfully tested in mice
October 15, 2000
Nasal administration of synthetic beta amyloid peptide reduces potentially damaging Alzheimer's disease-like plaques in the brains of test mice and may one day be tested in clinical trials for its ability to vaccinate against plaque...
NIA to study COX-2 inhibitor, other NSAID as new treatment for Alzheimer's disease
February 7, 2000
The National Institute on Aging (NIA) is launching a clinical trial to determine whether treatment with certain nonsteroidal anti-inflammatory drugs (NSAIDs) will slow cognitive and clinical decline in patients with Alzheimer's disease...
Low-dose prednisone found ineffective against Alzheimer's disease; researchers continue to look at NSAIDs, other drugs
February 7, 2000
A low-dose regimen of the steroid prednisone, an anti-inflammatory drug, is not effective in the treatment of Alzheimer's disease (AD), according to findings from a new clinical trial. The report, one of the first from a number of...
"Untangling" tau: New mouse model shows key feature of Alzheimer's disease
November 23, 1999
Scientists have succeeded in producing a hallmark of Alzheimer's disease in a laboratory animal model. The much-anticipated transgenic mouse model is genetically-engineered with the human gene coding for a form of the brain protein tau...
Gene that causes familial British dementia may yield clues to Alzheimer's disease
June 23, 1999
Researchers supported by the National Institute on Aging (NIA) have discovered a novel gene, which when mutated is responsible for familial British dementia (FBD), a rare inherited disease that causes progressive dementia like that seen in...
Study furthers understanding of critical Alzheimer's disease gene
April 7, 1999
Researchers have cracked part of the code for an important gene function in familial Alzheimer's disease (FAD), an early-onset type of AD. Alzheimer's disease is the most common cause of dementia. Working with cells in culture that...
Questions and answers on launch of NIA memory impairment study
March 15, 1999
1. What is Mild Cognitive Impairment? Mild cognitive impairment (MCI) is a condition characterized by memory impairment with otherwise unaffected cognitive functioning. 2. How can MCI be distinguished from normal forgetfulness? Normal...