NIH-supported international teams identify rare Alzheimer’s disease risk gene variant
November 15, 2012
Two international teams of researchers, with NIH scientists and support, have separately identified a rare variation in the TREM2 gene as a moderate risk factor for late-onset Alzheimer’s disease. TREM2 is a gene involved in...
NIH-supported scientists find genes influence susceptibility to problems from vitamin D deficiency
November 14, 2012
An international team of researchers has found that the vitamin D receptor gene (VDR), which senses and communicates the presence of vitamin D to the body, influences the chance that people with vitamin D deficiency develop negative health...
NIH Toolbox Unveiled
November 2, 2012
Standardized neurological, behavioral measures to aid clinical research Unveiled in September 2012, the NIH Toolbox for Assessment of Behavioral and Neurological Function provides common, standardized measurements that will make it...
Genetic variation linked to age-related hearing loss
October 25, 2012
A team of NIH-supported researchers has confirmed a link between age-related hearing loss and a gene producing a key protein in the inner ear. The findings reinforce observations in older people that genetics and environment interact,...
New database aims to capture international Alzheimer’s disease research efforts
October 10, 2012
NIH, Alzheimer’s Association invite research funders to participate A new, publicly available database is seeking to capture the full spectrum of current Alzheimer’s disease research investments and resources—both in...
NIA encourages applications to GEMSSTAR research program for early-career physicians moving into aging research
August 15, 2012
The NIA’s GEMSSTAR – Grants for Early Medical/Surgical Specialists' Transition to Aging Research – program is winning rave reviews for enabling physicians just starting out in their careers to connect their specialty...
Investigators create “brain map” of key epigenetic processes
August 14, 2012
Epigenetics, the study of how the environment modifies the way the human gene is expressed, is an emerging frontier in science. Diet and exposure to environmental chemicals, among other factors, can cause epigenetic changes that may turn...
Experimental Alzheimer’s drug shows promise in small, early-phase clinical studies
July 12, 2012
Posiphen, a drug candidate designed and developed by researchers in the NIA’s Intramural Research Program, has been shown in three small, early studies to be well-tolerated and to reduce the generation of amyloid and tau protein...
Clinical trials now recruiting
July 11, 2012
Numerous clinical trials and studies are currently recruiting participants with and without Alzheimer's disease, mild cognitive impairment or related dementias. NIA’s Alzheimer’s Disease Education and Referral (ADEAR)...
Exendin-4: From lizard to laboratory... and beyond
July 11, 2012
Throughout history, the natural world has served as a rich resource for compounds to treat human disease. For example, clay tablets from Mesopotamia dating from 2600 B.C.—humanity’s earliest written records—describe the...