Altered genes, altered metabolism - longer life?
August 14, 1997
Scientists supported by the National Institute on Aging (NIA) have discovered that a gene, named daf-2 , which regulates glucose (sugar) metabolism in a tiny worm, Caenorhabditis elegans , may also affect or enhance its longevity. The...
16-year study is further evidence that estrogen replacement may be protective against Alzheimer's disease
June 18, 1997
Scientists at the National Institute on Aging (NIA) and Johns Hopkins Bayview Medical Center have shown that a history of estrogen replacement therapy (ERT) in women after menopause was associated with a reduction, by over 50 percent, in...
New study finds substance that helps working memory work better
June 9, 1997
The drug, physostigmine, when administered to people by infusion in laboratory tests, aids and improves performance of everyday working memory. Working memory is the process which temporarily holds information such as a phone number until...
New drug therapies delay effects of Alzheimer's disease
April 23, 1997
Selegiline (or Eldepryl) and alpha-tocopherol (or Vitamin E) may slow important functional signs and symptoms of Alzheimer's disease by about 7 months, according to a report by scientists at 23 Alzheimer's Disease Cooperative Study...
Prostate cancer's aggressiveness may be predicted early by the ratio of free to total PSA
April 2, 1997
The ratio of free to total prostate specific antigen (PSA) in a man's blood may predict at the time of diagnosis whether prostate cancer will be an aggressive, fast-growing disease or a non-aggressive, slow-growing type of cancer. This...
Media campaign cautions consumers about "anti-aging" hormone supplements
April 1, 1997
The National Institute on Aging (NIA), part of the National Institutes of Health, is launching an education effort urging consumers to use caution when it comes to "anti-aging" hormone supplements that have become popular...
Disability rate among older Americans declines dramatically
March 17, 1997
America's elderly continue to defy negative stereotypes that aging is synonymous with increasing decline and disability. According to new findings from the National Long Term Care Surveys, disability rates among older people in the U.S...
New findings on Alzheimer's disease offer clues on causes, diagnosis, and treatments
March 11, 1997
Research on Alzheimer's disease is entering a new, highly productive phase and the pace of promising developments is accelerating, according to scientists at the National Institute on Aging (NIA). In an editorial examining important...
Anti-inflammatory drugs may help reduce risk of Alzheimer's disease
March 10, 1997
In a 15-year study, anti-inflammatory drugs such as ibuprofen, taken for as little as two years, appear to reduce the risk of Alzheimer's Disease (AD). Acetaminophen, with no anti-inflammatory activity, had no effect on the risk of AD...
Study suggests new way to reduce disability among the elderly
March 4, 1997
A new study by researchers at the National Institute on Aging (NIA) demonstrates that a small number of diseases and conditions that can lead to hospitalization-- stroke, hip fracture, congestive heart failure, pneumonia, coronary heart...
Prostate cancer may be predicted 10 years before diagnosis with repeated measures of free to total PSA
December 31, 1996
Repeated measures of the ratio of free to total prostate specific antigen (PSA) in a man's blood can predict a diagnosis of prostate cancer up to six years earlier than current prediction methods. This discovery by researchers at the...
Exercise - A safe and effective new treatment for knee osteoarthritis
December 31, 1996
Now there's scientific proof that exercise can be a safe and effective treatment option for knee osteoarthritis - good news for the millions of disabled Americans suffering from this degenerative joint disease. A recent clinical study,...
Low rates of Alzheimer's disease found in Cherokee Indians
October 14, 1996
The degree to which Cherokee Indians are of pure ancestry or mixed ancestry may play a role in delaying the development of Alzheimer's disease after age 65. Research by National Institute on Aging (NIA) grantees at the University of Texas...
Scientists develop mouse model for Alzheimer's disease
October 3, 1996
A new mouse model that will further understanding of Alzheimer's disease and ultimately allow for testing of drug therapies has been developed by scientists at the University of Minnesota. The genetically-engineered mouse is the first to...
Study yields new clues for Alzheimer's disease
September 24, 1996
Several recent studies have begun to define the involvement of certain genes in the development of Alzheimer's disease. But a new study comparing the occurrence of dementia and Alzheimer's disease among different populations...
Estrogen and delayed onset of Alzheimer's disease
August 16, 1996
National Institute on Aging (NIA)-supported scientists at Columbia-Presbyterian Medical Center suggest that estrogen therapy taken by post-menopausal women may significantly delay the onset of Alzheimer's disease. Results of the study...
A gene involved in regulating longevity in worms may provide a clue to human aging
August 8, 1996
Discovery of a mutant gene involved in the regulation of longevity of a primitive worm, C. elegans, may provide a clue as to how humans age. Normal development and longevity in the worm C. elegans are regulated by the age-1 gene. Lack of...
Exercise can boost cardiac fitness in conditioned and out-of-shape older people
August 2, 1996
It may not be too late to benefit from exercise, even for people in their 60's and older, according to scientists at the National Institute on Aging (NIA) Gerontology Research Center, the Johns Hopkins Medical Institutions, and the...
Tai chi for older people reduces falls, may help maintain strength
May 2, 1996
Tai Chi, a martial arts form that enhances balance and body awareness through slow, graceful, and precise body movements, can significantly cut the risk of falls among older people and may be beneficial in maintaining gains made by people...
New findings suggest how caloric restriction may prolong healthy life
April 29, 1996
Researchers at the National Institute on Aging's (NIA) Gerontology Research Center (GRC) have shown for the first time that reducing calorie intake by 30 percent lowers body temperature in monkeys. This lowered body temperature is a result...