Skip to main content
Featured Research

Some brain functions may improve with age

Repost from NIH Research Matters

Cognitive changes such as mild forgetfulness are often a normal part of aging. Older adults may find that it takes longer to remember a fact or learn a new skill. At the extreme end, the risk of dementia rises with aging. For example, the number of people with Alzheimer’s disease doubles about every 5 years beyond age 65.

Older woman sitting at home using a laptop and reviewing papers.But not all brain functions are thought to decline with age. Cognitive skills that require constant practice, such as understanding and using language, are usually well preserved. Researchers have wondered whether some cognitive skills may actually improve with age.

To look more closely at this question, a team led by Dr. João Veríssimo from the University of Lisbon in Portugal and Dr. Michael Ullman from Georgetown University studied more than 700 older adults aged 58 to 98. The participants were part of the Social Environment and Biomarkers of Aging Study in Taiwan, which explored the relationship between life challenges and mental, physical, and cognitive health in older age.

In one part of the study, people took computerized tests of three aspects of attention. The first was being prepared to respond to incoming information (alerting). The second was moving attention to a particular location (orienting). The third was executive control—the ability to ignore distractions and focus on the task at hand.

The researchers measured differences in these three abilities between participants across the age range they studied. They adjusted for factors such as sex, education, and visual abilities. The study was funded in part by NIH’s National Institute on Aging (NIA). Results were published on August 19, 2021, in Nature Human Behaviour.

Overall, increasing age was associated with slower response times. Aging was also associated with less alertness to incoming information. However, the other two aspects of attention studied showed improvements with age. Older participants had increased efficiency in their ability to orient attention toward different objects. They were also better at ignoring distractions than younger participants.

These two preserved brain functions showed different trajectories over time. The ability to orient attention increased steadily from middle age into older adulthood. The ability to ignore distractions and focus on relevant information increased into the mid-to-late 70s, then declined. However, the gains from earlier old age were substantial enough so that even the oldest adults were no worse at ignoring distractions than the youngest.

“People have widely assumed that attention and executive functions decline with age,” Ullman says. “But the results from our large study indicate that critical elements of these abilities actually improve during aging, likely because we simply practice these skills throughout our life.”

The improvements found in brain functions may have benefits for higher-level cognitive abilities, such as decision-making and long-term memory. More research is needed to see if targeting such skills could help protect against overall cognitive decline during aging.

by Sharon Reynolds

This research is supported by NIH grants R01AG016790 and R01AG016661.

Reference: Evidence that ageing yields improvements as well as declines across attention and executive functions. Veríssimo J, et al. Nat Hum Behav. 2021 Aug 19. doi: 10.1038/s41562-021-01169-7. Online ahead of print. PMID: 34413509.