Lewy Body Dementia Research
There is a great deal to learn about Lewy body dementia (LBD). At a basic level, why does alpha-synuclein accumulate into Lewy bodies, and how do Lewy bodies cause the symptoms of LBD? LBD represents an important link between Alzheimer's, Parkinson's, and other brain disorders, and research into one disease often contributes to better understanding of the others.
Many avenues of research focus on improving our understanding of LBD. Some researchers are working to identify the specific differences in the brain between dementia with Lewy bodies and Parkinson's disease dementia. Others are looking at the disease's underlying biology, genetics, and environmental risk factors. Still other scientists are trying to identify biomarkers (biological indicators of disease), improve screening tests to aid diagnosis and research new treatments.
Scientists hope that new knowledge about LBD will one day lead to more effective treatments and even ways to cure and prevent the disorder. Until then, researchers need volunteers with and without LBD for clinical studies.
NIH and other groups help people learn about clinical trials and studies and find research opportunities near them. Visit the following websites for details:
- National Institute on Aging (search using the keyword "Lewy" or the category "Related Dementias")
- Lewy Body Dementia Association
- National Institutes of Health
For More Information About Lewy Body Dementia Research
NIA Alzheimer’s and related Dementias Education and Referral (ADEAR) Center
The National Institute on Aging’s ADEAR Center offers information and free print publications about Alzheimer’s disease and related dementias for families, caregivers, and health professionals. ADEAR Center staff answer telephone, email, and written requests and make referrals to local and national resources.
Lewy Body Dementia Association
1-844-311-0587 (toll-free LBD Caregiver Link)
Michael J. Fox Foundation for Parkinson's Research
Content reviewed: June 27, 2018