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Related Dementias

Lewy Body Dementia Research

There is a great deal to learn about Lewy body dementia (LBD). At a basic level, why does alpha-synuclein accumulate into Lewy bodies, and how do Lewy bodies cause the symptoms of LBD? It is also of increasing interest to the Alzheimer’s and Parkinson’s disease research communities. LBD represents an important link between these other brain disorders, and research into one disease often contributes to better understanding of the others.Researcher next to lab equipment

Many avenues of research focus on improving our understanding of LBD. Some researchers are working to identify the specific differences in the brain between dementia with Lewy bodies and Parkinson’s disease dementia. Others are looking at the disease’s underlying biology, genetics, and environmental risk factors. Still other scientists are trying to identify biomarkers (biological indicators of disease), improve screening tests to aid diagnosis and research new treatments.

Scientists hope that new knowledge about LBD will one day lead to more effective treatments and even ways to cure and prevent the disorder. Until then, researchers need volunteers with and without LBD for clinical studies.

To find out more about clinical trials, talk with a doctor or visit the National Institutes of Health Web site. To find clinical trials and studies, search the NIA's Clinical Trials Database.

For More Information About Lewy Body Dementia Research

NIA Alzheimer’s and related Dementias Education and Referral (ADEAR) Center
1-800-438-4380 (toll-free)
adear@nia.nih.gov
www.nia.nih.gov/alzheimers
The National Institute on Aging’s ADEAR Center offers information and free print publications about Alzheimer’s disease and related dementias for families, caregivers, and health professionals. ADEAR Center staff answer telephone, email, and written requests and make referrals to local and national resources.

Lewy Body Dementia Association
1-404-935-6444
1-800-539-9767 (toll-free LBD Caregiver Link)
www.lbda.org

National Institute of Neurological Disorders and Stroke
1-800-352-9424 (toll-free)
braininfo@ninds.nih.gov
www.ninds.nih.gov

Michael J. Fox Foundation for Parkinson's Research
1-800-708-7644 (toll-free)
www.michaeljfox.org

Parkinson's Disease Foundation
1-800-457-6676 (toll-free)
info@pdf.org
www.pdf.org