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Causes of Alzheimer's Disease

Scientists believe that a combination of genetic, lifestyle, and environmental factors influence when Alzheimer’s disease begins and how it progresses. 

Watch a video about how Alzheimer's changes the brain.

In the News

Articles

What Causes Alzheimer's Disease?

How does Alzheimer's disease affect the brain? Read how genetics, environment, and lifestyle play a role in developing early- or late-onset Alzheimer’s.
DNA strand

Assessing Risk for Alzheimer's Disease

What are risk factors for Alzheimer’s disease? Learn about genetic and other risks for early- and late-onset Alzheimer's and steps you can take to stay healthy.
African-american family

Alzheimer's Disease Genetics Fact Sheet

Read about the genetics of Alzheimer's disease. A genetic mutation can cause early-onset Alzheimer's. In late-onset Alzheimer's, a variant of the APOE gene increases risk.
diagram of gene showing cell, chromosome, and DNA

Alzheimer's Disease in People with Down Syndrome

Many, but not all, people with Down syndrome develop Alzheimer's disease when they get older. Learn about the connection between the two and how to participate in research studies exploring this relationship.
Middle aged adult with Down Syndrome