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  1. Preventing Loss of Independence Through Exercise in Veterans with Dementia (PLIE)

    Preventing Loss of Independence Through Exercise in Veterans with Dementia (PLIE) Overall Status:  ... Recruiting Brief Description:  This clinical trial will test a novel exercise program, Preventing Loss of ... ID  NCT02350127 (follow link to view full record on ct.gov in new window) Official Title:  Preventing ...

    chirschman - 03/21/2017 - 15:00

  2. Behavioral Interventions to Prevent or Delay Dementia

    Behavioral Interventions to Prevent or Delay Dementia Overall Status:  Recruiting Brief ... take part in four of these five behavioral interventions for 10 days during the course of 2 weeks: ... minutes per day; participant will be part of reminiscence-focused group sessions. Wellness education: ...

    chirschman - 03/09/2017 - 10:31

  3. Brain Changes with Game Training in Aging

    mild Alzheimer's disease with predominant amnesia Detailed Description:  Recent neuroimaging ... training therapies to prevent or slow cognitive decline. Locations:  Map Marker   City State Zip Code ...

    chirschman - 03/09/2017 - 11:25

  4. Down Syndrome Memantine Follow-up Study

    part in an optional magnetic resonance imaging (MRI) study, aimed at making the EEG study more precise ... preclinical research on Alzheimer's disease: update on recent advances. Pharmacol Biochem Behav. 2012 ... Correa A; National Birth Defects Prevention Network. Updated National Birth Prevalence estimates for ...

    chirschman - 03/10/2017 - 14:33

  5. Mild Cognitive Impairment in Breast Cancer

    on annual examinations done as part of the NIA Alzheimer's Disease Centers (ADC) program Recruited from the ... developing treatment-related cognitive impairment is needed to develop potential prevention or treatment ... options and prevent further decline. Although neuroimaging studies have identified brain changes ...

    chirschman - 03/20/2017 - 12:07

  6. Alzheimer's Prevention Registry

    Alzheimer's Prevention Registry Overall Status:  Recruiting Brief Description:  The ... Alzheimer's Prevention Registry is a national registry of individuals age 18 and older who are interested in ... learning about and possibly participating in Alzheimer's prevention clinical studies and trials. The ...

    chirschman - 03/08/2017 - 16:57

  7. Mediterranean Diet to Prevent Cognitive Decline

    Mediterranean Diet to Prevent Cognitive Decline Overall Status:  Recruiting Brief Description:  ... window) Official Title:  Feasibility Trial of a Mediterranean Diet Pattern to Prevent Cognitive Decline ...

    chirschman - 11/15/2016 - 09:04

  8. Telmisartan to Prevent Alzheimer's in African Americans

    Telmisartan to Prevent Alzheimer's in African Americans Overall Status:  Recruiting Brief ... blood pressure, may help prevent Alzheimer's disease in African Americans, a group at relatively ...

    chirschman - 03/22/2017 - 13:17

  9. Early Detection and Prevention of Mild Cognitive Impairment Due to Cerebrovascular Disease

    Early Detection and Prevention of Mild Cognitive Impairment Due to Cerebrovascular Disease Overall ... factors can prevent such problems. Participants will be randomly chosen to be followed naturally by ... how vascular risk factors cause memory and thinking changes in the elderly, and whether we can prevent ...

    chirschman - 03/10/2017 - 14:43

  10. MIND Diet to Prevent Cognitive Decline

    MIND Diet to Prevent Cognitive Decline Overall Status:  Recruiting Brief Description:  This study ... window) Official Title:  MIND Diet Intervention to Prevent Alzheimer's Disease Study Start Date:  ...

    jharper - 01/31/2017 - 09:18

  11. Sleep-Disordered Breathing and Alzheimer's Disease Prevention (SNAP)

    Sleep-Disordered Breathing and Alzheimer's Disease Prevention (SNAP) Overall Status:  ... Elderly and Alzheimer's Disease Prevention (SNAP) Study Study Start Date:  July 2013 Study End Date:  ...

    chirschman - 03/22/2017 - 11:46

  12. CAD106 and CNP520 to Prevent or Delay Symptoms of Alzheimer's Disease (Generation)

    CAD106 and CNP520 to Prevent or Delay Symptoms of Alzheimer's Disease (Generation) Overall ... CAD106 and CNP520, administered separately, can prevent or delay Alzheimer's disease symptoms in ... prevent the production of different forms of amyloid. Participants will also undergo at least two positron ...

    chirschman - 03/10/2017 - 12:24

  13. Alzheimer's Prevention Through Exercise

    Alzheimer's Prevention Through Exercise Overall Status:  Recruiting Brief Description:  The ...

    chirschman - 03/08/2017 - 16:59

  14. Cognitive Training to Prevent Postoperative Delirium

    Cognitive Training to Prevent Postoperative Delirium Overall Status:  Recruiting Brief ... Prevention of Postoperative Delirium: a Pilot Study Study Start Date:  December 2016 Study End Date:  ...

    jharper - 01/31/2017 - 09:39

  15. GeneMatch

    GeneMatch Overall Status:  Recruiting Brief Description:  The GeneMatch program, part of the ... Alzheimer's Prevention Registry, aims to identify people interested in participating in research studies or ... clinical trials based in part on their genetic background. GeneMatch will collect genetic information from ...

    chirschman - 03/22/2017 - 16:00

  16. Treatment of Psychosis and Agitation in Alzheimer's Disease

    J, Pallás M. Potential mechanisms involved in the prevention of neurodegenerative diseases by ... study. J Clin Psychiatry. 2009 Jun;70(6):922-31. Katz I, de Deyn PP, Mintzer J, Greenspan A, Zhu Y, ...

    chirschman - 03/22/2017 - 13:23

  17. Mindfulness-Based Stress Reduction, Health Education, and Exercise

    part of aging Sedentary Detailed Description:  Participants will be randomly assigned to one of four ... practices appear to produce neurocircuitry changes that may prevent age-related cognitive decline. There ...

    chirschman - 03/20/2017 - 12:14

  18. Neurotrack Test Validation

    diagnosis based on recent (within 1 year) consensus meeting and neuropsychological test scores Cognitively ...

    chirschman - 03/23/2017 - 10:15

  19. LY3002813 for Mild Cognitive Impairment or Alzheimer's Disease

    disease. The study involves three parts. In Part A, participants will receive a single dose of LY3002813 or ... a placebo, administered intravenously. In Part B, they will receive multiple doses of the drug or a placebo ... for 24 weeks (about 6 months). In Part C, they will receive multiple doses of LY3002813 or a placebo ...

    chirschman - 03/20/2017 - 11:47

  20. Trial of Oxaloacetate in Alzheimer's Disease (TOAD)

    throughout the trial Detailed Description:  Researchers believe mitochondria, the part of cells that produces ... changes in brain gluclose metabolism and other brain changes. The study is divided into two parts. In the ... first part, 15 participants will take 1 gram per day of oxaloacetate for approximately 4 weeks. After it ...

    chirschman - 03/22/2017 - 13:24

  21. Reasoning Training in Individuals with Mild Cognitive Impairment

    part in intervention Women must be postmenopausal Detailed Description:  Participants will be randomly ... treatment that uses direct electrical currents to stimulate specific parts of the brain. A constant, ...

    chirschman - 03/22/2017 - 10:18

  22. ENGAGE: Aducanumab (BIIB037) for Early Alzheimer's Disease

    Geolocation is 46.8371449,-71.226169 CHU de Quebec- Hôpital de l' Enfant Jésus Quebec G1J 1Z4 Recruiting ...

    chirschman - 03/13/2017 - 13:00

  23. 18F-AV-1451 Autopsy Study

    25.733888,-80.4604643 D de la Vega MD Research Group Miami Florida 33185 Suspended n/a Geolocation is ...

    chirschman - 04/17/2017 - 21:00

  24. Dietary Flavanols and Dentate Gyrus Function

    function related to the dentate gyrus, a part of the brain thought to contribute to the formation of new ...

    chirschman - 03/10/2017 - 14:20

  25. Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment

    MRI-compatible if taking part in functioinal MRI studies Diagnosis of amnestic MCI based on criteria set forth by ...

    chirschman - 03/22/2017 - 10:13

  26. EEG Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENGAGES)

    electroencephalography (EEG)-guided anesthesia protocol can prevent delirium after surgery and improve patients' ... intervention for delirious patients prevents adverse events. Locations:  Map Marker   City State Zip Code ...

    chirschman - 03/10/2017 - 14:44

  27. MindCrowd

    Alzheimer's Prevention Initiative Facility Investigators:  Name Role Affiliation Matt Huentelman Principal ...

    chirschman - 05/06/2015 - 16:16

  28. Repetitive Transcranial Magnetic Stimulation for Apathy in Alzheimer's Dementia

    a non-invasive way to stimulate parts of the brain using a magnet. Participants will be randomly chosen to ...

    chirschman - 03/02/2016 - 06:30

  29. Candesartan vs. Lisinopril Effects on the Brain (CALIBREX)

    Test, Part B (TMT-B), modified Stroop interference, verbal fluency (number of D words in 1 minute) or ...

    chirschman - 03/10/2017 - 12:39

  30. Enhancing Spatial Navigation with Noninvasive Brain Stimulation

    native and preferred language Ablity to undergo magnetic resonance imaging  (MRI) if taking part in fMRI ...

    chirschman - 03/13/2017 - 13:27

  31. Dietary Intervention in Cognitive Aging

    goal is to develop interventions that might forestall or prevent progression of neurocognitive decline ...

    chirschman - 06/01/2016 - 12:04

  32. Memory and Thinking Problems in Older Adults After Surgery

    interventions during surgery that will prevent neurodegenerative disease acceleration. Locations:  Map Marker ...

    chirschman - 03/20/2017 - 11:55

  33. Neuropsychological Test Validation Project

    facilitate Alzheimer's disease prevention clinical trials. The tools, developed by CogState and ...

    chirschman - 03/21/2017 - 11:00

  34. Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

    factors. For this study, participants will take part in a medical history, physical exam, blood and urine ...

    chirschman - 03/13/2017 - 14:12

  35. Brain Health Registry

    function through the prevention of brain diseases, disorders, and injuries in adults. Participation ...

    chirschman - 03/10/2017 - 12:20

  36. BDPP Treatment for Mild Cognitive Impairment and Prediabetes

    a Bioactive Dietary Polyphenol Preparation (BDPP), to see if it can improve cognition and delay or prevent ...

    chirschman - 04/24/2017 - 22:00

  37. Dominantly Inherited Alzheimer Network (DIAN)

    optional participant benefit and are not part of the DIAN research design. Locations:  Map Marker   City ...

    admin - 03/10/2017 - 14:29

  38. Brain Aging in Vietnam War Veterans (DOD-ADNI)

    veterans with histories of TBI and PTSD, and a possible need to employ prevention and treatment measures to ... a larger, more comprehensive study of dementia risk factors in veterans and design of a trial to prevent ...

    chirschman - 03/22/2017 - 16:00

  39. Imaging Dementia—Evidence for Amyloid Scanning (IDEAS) Study

    also assess the impact of amyloid PET results on clinical diagnosis and prevention of unnecessary ...

    chirschman - 09/30/2016 - 12:03

  40. Piromelatine for Mild Alzheimer's Disease (ReCOGNITION)

    cognition, and mood, in part by improving sleep quality, in people with mild Alzheimer's dementia. ...

    chirschman - 03/22/2017 - 16:00