Start:
February 19, 2020
End:
December 2023
Enrollment:
30
Transcranial magnetic stimulation (TMS) is a safe and noninvasive means of electrically stimulating the brain using a magnet. noninvasive way to stimulate the brain. Constrained induced language therapy (CILT) is a therapy that allows only verbal communication and has been used to treat verbal communication problems after a stroke or in people with dementia. This study will test the effects of combining TMS and verbal language therapy on improving language and speaking abilities in people with Alzheimer's disease. Each study participant will begin with three treatment sessions, lasting one to two hours each, depending on the comfort of the participant. In addition, each participant will receive an MRI scan of the brain or a CAT scan of the head, as appropriate. During the two-week treatment phase, each participant will receive 10 TMS sessions with CILT therapy or a sham. In follow-up, there will be two three-month post-treatment visits and two six-month post-treatment visits for final language and cognitive tests and a final MRI or CT scan.
Minimum Age: 60 Years
Maximum Age: 85 Years
Contact study personnel listed either under the general study contact or the location nearest you.
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.
Pennsylvania | |
---|---|
University of Pennsylvania
Philadelphia,
PA
19104
Recruiting
Research Coordinator |
Lead: University of Pennsylvania
Collaborator Sponsor
Source: ClinicalTrials.gov ID: NCT04482179
An official website of the U.S. government, managed by the National Institute on Aging at the National Institutes of Health