Tau PET Imaging and Cognition
Recruiting
This study will use the new radioactive tracer 18F-MK-6240 in positron emission tomography (PET) scanning to detect tau pathology in older adults who are cognitively healthy and mildly cognitively impaired.
| Minimum Age | Maximum Age | Gender | Healthy Volunteers |
|---|---|---|---|
| 55 Years | 90 Years | All | Yes |
- Participation in amyloid PET scanning study
- Reside near Columbia University Medical Center
- Willing and able to participate
- Inability to undergo PET, such as metallic implants, pacemaker, claustrophobia, or difficulty lying flat for one hour
- Pregnant or lactating
- Current, past, or anticipated exposure to radiation
- Significant active physical illness
Tau is a protein that accumulates abnormally in the brains of people with Alzheimer's disease and other dementias. In this study researchers will examine the interactions between tau levels and performance on cognitive tasks, functional magnetic resonance imaging neural activation patterns, and other cognitive and behavioral measures. The study also aims to examine how the presence of tau may contribute to the risk of subsequent cognitive decline, neurodegeneration, and dementia.
| Name | City | State | Zip | Status | Primary Contact |
|---|---|---|---|---|---|
|
Columbia University Medical Center |
New York | New York | 10032 | Recruiting |
Ann Ann Ohkawa 212-305-6314 ao2454@cumc.columbia.edu |
Yaakov Stern
- National Institute on Aging (NIA)
| Name | Role | Affiliation |
|---|---|---|
| Yaakov Stern, PhD | Principal Investigator | Columbia University |
| Name | Phone | |
|---|---|---|
| Ann Ohkawa | 212-305-6314 | ao2454@cumc.columbia.edu |
| Ashley Mensing, BS | 212-305-6314 | anm2186@cumc.columbia.edu |
Tau Positron Emission Tomography (PET) in Imaging and Cognition