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Tai Ji Quan and Cognitive Function in Mild Cognitive Impairment


This study will compare the effects of a cognitively enhanced tai ji quan intervention with standard tai ji quan and light exercise in older adults with mild cognitive impairment.

Minimum Age Maximum Age Gender Healthy Volunteers
65 Years N/A All No
October 15, 2019
December 2023

  • Complaint of memory loss
  • No or very mild dementia (Clinical Dementia Rating Scale score of 0.5 or less)
  • Normal general cognitive function (Mini-Mental State Examination score of 24 or more)
  • Capable of exercising safely, as determined by a healthcare provider

  • Having medical conditions likely to compromise survival or prevent physical activity, such as metastatic cancer or severe heart failure
  • Participating in any type of tai ji quan or daily and/or structured vigorous physical activity (e.g., brisk walking for 30 minutes or longer or weight lifting on 3 or more days per week) 3 months prior to the study

Tai ji quan, also known as tai chi, is a mind and body practice involving certain postures, gentle movements, and breathing techniques. In this study participants will either complete a cognitively enhanced tai ji quan intervention (Tai Ji Quan: Moving to Maintain Brain Health) or regular tai ji quan or light exercise activities (i.e., breathing, stretching, and body relaxation) for 24 weeks. Researchers will compare the effects of each intervention on changes in cognitive function and dual-task ability, which is the ability to perform two or more cognitive and motor activities simultaneously while maintaining postural control.

Name City State Zip Status Primary Contact
Oregon Research Institute
Eugene Oregon 97403 Recruiting Fuzhong Li, Ph.D.

Oregon Research Institute

Name Role Affiliation
Fuzhong Li, Ph.D. Principal Investigator Oregon Research Institute

Name Phone Email
Fuzhong Li, Ph.D. 541-484-2123


Efficacy of Adapted Tai Ji Quan to Slow Cognitive Decline in Older Adults