Start:
May 2014
End:
August 2015
Enrollment:
44
What Is This Study About?
This study will assess the effects of taking a strawberry supplement in older adults. Researchers hypothesize that plant compounds in strawberries may improve cognition and mobility by protecting against oxidative stress and inflammation.
Do I Qualify To Participate in This Study?
Must have:
- Body mass index of 18.5–29.9 kg/m2
- Adequate seeing ability to read and perform computer tasks
- Fluency in spoken and written English
- Ability to walk independently for 20 minutes
- For female participants, absence of menstruation for at least 12 months or surgical menopause
Must NOT have:
- Self-reported vegetarian or vegan
- Any condition that has resulted in cognitive deficits, including but not limited to Alzheimer's disease or other dementias, cerebrovascular accident, or head injury
- History of any neurologic disorder resulting in permanent or relapsing/remitting neurologic impairment, including but not limited to Parkinson's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, peripheral neuropathy, or radiculopathy
- History of any condition resulting in permanent muscle or mobility deficit that would interfere with walking independently for 20 minutes, including but not limited to amputation, fracture, arthritis, myopathy, or limb, hip, or back surgery within the last year
- Self-reported cognitive, memory, neurologic, or functional deficits that interfere with activities of daily living or functional status
- Any chronic condition associated with increased risk of falls, such as vestibular disease, orthostatic hypotension, or neuropathy
- Falls within the last year that occurred in the course of routine daily activities, not caused by circumstances such as being pushed or falling on ice
- Regular use of medications or dietary supplements known or suspected to influence cognitive function, attention, walking ability, gait, balance, or risk of falls that, in the opinion of the study physician, may influence study results or increase the risk of study participation
- Psychiatric disorders that could interfere with study testing, including bipolar disorder, psychosis, and major depression
- Mini-Mental State Examination score of less than 24 at screening (no dementia)
- Gastrointestinal disorders that influence digestion and absorption of food
- Diabetes mellitus
- Liver dysfunction or history of cirrhosis, as indicated by elevated levels of SGPT, SGOT, or total bilirubin
- Kidney disease, as indicated by serum creatinine more than 1.5 mg/dL at screening
- Cardiac or pulmonary conditions that limit ambulation or result in shortness of breath while walking
- Reported allergy to strawberries or ingredients in the placebo
- Average alcohol consumption of more than: two 12-oz. servings of beer, two 5-oz. servings of wine, or two 1.5-oz. servings of liquor, or self-reported binge-drinking
- Illicit drug use in the last 12 months
- Cigarette smoking in the last 6 months or current use of nicotine
Need Help?
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at
800-438-4380
or
email ADEAR.
Where Is This Study Located?
Collaborator Sponsor
-
California Strawberry Commission
Source:
ClinicalTrials.gov ID:
NCT02051140